Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8BVF7 | Aph1a | Gamma-secretase subunit APH-1A (APH-1a) (Aph-1alpha) | Mus musculus (Mouse) | 265 aa |
Protein Details: Q8BVF7 (Aph1a)
Protein Information
| Accession | Q8BVF7 |
|---|---|
| Protein Names | Gamma-secretase subunit APH-1A (APH-1a) (Aph-1alpha) |
| Gene Symbol | Aph1a |
| Organism | Mus musculus (Mouse) |
| Length | 265 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31772009 37925639 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGAAVFFGCT11FVAFGPAFSL21FLITVAGDPL31RVIILVAGAF41FWLVSLLLAS
51-10051VVWFILVHVT61DRSDARLQYG71LLIFGAAVSV81LLQEVFRFAY91YKLLKKADEG
101-150101LASLSEDGRS111PISIRQMAYV121SGLSFGIISG131VFSVINILAD141ALGPGVVGIH
151-200151GDSPYYFLTS161AFLTAAIILL171HTFWGVVFFD181ACERRRYWAL191GLVVGSHLLT
201-250201SGLTFLNPWY211EASLLPIYAV221TVSMGLWAFI231TAGGSLRSIQ241RSLSCRRQED
251-265251SRVMVYSALR261IPPED
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 9 | Gamma-secretase subunit Aph-1 | - | - |
Deep-Palm: 0.02
|
|
| 182 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.72
|
|
| 245 | - | - | - |
Deep-Palm: 0.94
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
3
Liver
Specificity: 0.750
3/3 (100.0%)
1
NSC
Specificity: 0.250
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.