Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8BWF0 | Aldh5a1 | Succinate-semialdehyde dehydrogenase, mitochondrial (EC 1.2.1.24) … | Mus musculus (Mouse) | 523 aa |
Protein Details: Q8BWF0 (Aldh5a1)
Protein Information
| Accession | Q8BWF0 |
|---|---|
| Protein Names | Succinate-semialdehyde dehydrogenase, mitochondrial (EC 1.2.1.24) (Aldehyde dehydrogenase family 5 member A1) (NAD(+)-dependent succinic semialdehyde dehydrogenase) |
| Gene Symbol | Aldh5a1 |
| Organism | Mus musculus (Mouse) |
| Length | 523 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29733200 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MATCFLLRSF11WAARPALPPP21GRFRPEPAGT31PRRSYASGPG41GLHADLLRGD
51-10051SFVGGRWLPA61PATFPVYDPA71SGAKLGTVAD81CGVPEARAAV91RAAYDAFNSW
101-150101KGVSVKERSL111LLRKWYDLMI121QNKDDLAKII131TAESGKPLKE141AQGEILYSAL
151-200151FLEWFSEEAR161RIYGDIIYTS171AKDKRGLVLK181QPVGVAAIIT191PWNFPSAMIT
201-250201RKVGAALAAG211CTVVVKPAED221TPYSALALAQ231LANQAGIPAG241VYNVIPCSRN
251-300251KAKEVGEVLC261TDPLVSKISF271TGSTATGKIL281LHHAANSVKR291VSMELGGLAP
301-350301FIVFDSANVD311QAVAGAMASK321FRNAGQTCVC331SNRFLVQRGI341HDSFVTKFAE
351-400351AMKKSLRVGN361GFEEGTTQGP371LINEKAVEKV381EKQVNDAVAK391GATVVTGGKR
401-450401HQSGGNFFEP411TLLSNVTRDM421LCITEETFGP431LAPVIKFDKE441EEAVAIANAA
451-500451EVGLAGYFYS461QDPAQIWRVA471EQLEVGMVGV481NEGLISSVEC491PFGGVKQSGL
501-523501GREGSKYGID511EYLEVKYVCY521GGL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 4 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.04
|
|
| 81 | SWISSPALM DBPTM CYSMODDB | Aldehyde dehydrogenase family |
Liver
(28526873)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.92
Deep-Palm: 0.98
|
| 211 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.97
|
|
| 247 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.95
|
|
| 260 | SWISSPALM DBPTM CYSMODDB | Aldehyde dehydrogenase family |
brain
(39008777)
Liver
(28526873)
|
Liver
(34884899)
Brain
(35358180)
|
Deep-Palm: 0.96
|
| 328 | Aldehyde dehydrogenase family |
brain
(39008777)
|
Brain
(35358180)
|
GPS-Palm: 0.93
Deep-Palm: 0.88
|
|
| 330 | Aldehyde dehydrogenase family |
brain
(39008777)
|
Brain
(35358180)
|
GPS-Palm: 0.93
Deep-Palm: 0.75
|
|
| 422 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.97
|
|
| 490 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.95
|
|
| 519 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.95
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
6
Liver
Specificity: 0.146
6/6 (100.0%)
4
Brain
Specificity: 0.098
4/4 (100.0%)
2
Testis
Specificity: 0.049
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
29
Brain tissue (Mass)
Specificity: 0.707
29/56 (51.8%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.