Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8BWN8 Acot4 Peroxisomal succinyl-coenzyme A thioesterase (EC … Mus musculus (Mouse) 421 aa

Protein Details: Q8BWN8 (Acot4)

Protein Information
AccessionQ8BWN8
Protein NamesPeroxisomal succinyl-coenzyme A thioesterase (EC 3.1.2.3) (Acyl-coenzyme A thioesterase 4) (Acyl-CoA thioesterase 4) (PTE-2b) (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-CoA thioesterase Ib) (PTE-Ib)
Gene SymbolAcot4
OrganismMus musculus (Mouse)
Length421 aa
IsoformsNo isoforms
Related PMIDs 28526873 34200797 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAATLSVEPT11GRSCWDEPLS21IAVRGLAPEQ31PVTLRSVLRD41EKGALFRAHA
51-10051RYRADSHGEL61DLARVPALGG71SFSGLEPMGL81LWAMEPDRPF91WRLIKRDVQT
101-150101PFLVELEVLD111GHEPDGGRRL121ARTVHERHFM131APGVRRVPVR141EGRVRATLFL
151-200151PPGQGPFPGI161IDVYGVGGGL171LEYRAGLVAG181HGFATLALAF191YDFEDLPKEL
201-250201NVIEVDYFEE211AVRYMLRHPK221VKGPDIGLLG231LSLGADVCLI241MASFLNNVSA
251-300251TVSINGSAFS261GNRHIKYKQT271MIPPLGHDLR281RMKVAFSGIL291DIVDIRNDAV
301-350301GGCENPSMIP311IEKAKGPILF321VAGQDDHCWR331SELYTQIASD341RLQAHGKERP
351-400351QVLSYPGTGH361YIEPPYFPMC371PASLHKIVNE381AVIWGGEVKA391HSKAQIDAWK
401-421401QILFFFGKHL411GSTHSRASCR421L
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
14 Acyl-CoA thioester hydrolase/BAAT, N-terminal
Brain (34200797)
Brain (35358180)
Deep-Palm: 0.94
238 - - -
Deep-Palm: 0.98
303 SWISSPALM DBPTM CYSMODDB BAAT / Acyl-CoA thioester hydrolase C terminal
Liver (28526873)
-
Deep-Palm: 0.77
328 - - -
Deep-Palm: 0.95
370 - - -
Deep-Palm: 0.25
419 - - -
GPS-Palm: 0.93
Deep-Palm: 0.02
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
Liver
Specificity: 0.800
4/4 (100.0%)
1
Brain
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine