Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8C145 Slc39a6 Zinc transporter ZIP6 (Endoplasmic reticulum … Mus musculus (Mouse) 765 aa

Protein Details: Q8C145 (Slc39a6)

Protein Information
AccessionQ8C145
Protein NamesZinc transporter ZIP6 (Endoplasmic reticulum membrane-linked protein) (Ermelin) (Solute carrier family 39 member 6) (Zrt- and Irt-like protein 6) (ZIP-6)
Gene SymbolSlc39a6
OrganismMus musculus (Mouse)
Length765 aa
IsoformsNo isoforms
Related PMIDs 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MATDLSVIMI11LTFALWVTSP21LHELQSTAAF31SQTTEKINSN41WEPGVNVDLA
51-10051VTMQRHHLQQ61LFYRYGENDS71LSVEGFRKLL81QNIGIDKIKR91VHIHHDHEHH
101-150101ADHEHHSDHE111HHSDHEHHSD121HEHHSDHEHH131SDHEHHSHRS141HTVAGKNNRK
151-200151AFCPDLDSDN161SGKNPRTSLG171KGSRPAEHMN181GRRNIKESAS191SSEVTSAVYN
201-250201AVSEGTRFVE211TIETPKPGRR221TKDVNPSTPP231SITEKSRVGR241LSRLARKKSN
251-300251ESVSEPRKSF261MYSRNTNDNI271QECFNTTKLL281TSHGMSIQAL291LNATEFNYLC
301-350301PAIINQIDAR311ACLIHTASEK321KAEIPPKTYS331LQIAWLGGFI341AISIISFLSL
351-400351LGVILVPLMN361RVFFKFLLSF371LVALAVGTLS381GDALLHLLPH391SHASHQHSHS
401-450401HEEPAMEMKR411GPLFSHLSAQ421NIEESSYFDS431TWKGLTALGG441LYFMFLVEHV
451-500451LTLIKQFKDK461KKKNQKKPEN471DEDVESKKQL481SKYDSQLSSN491EEKVDPGERP
501-550501ESYLRADSQE511PSPFDSQQPT521MLEEEEVMIA531HAHPQEVYNE541YVPRGCKNKC
551-600551HSHFHDTLGQ561SDDLIHHHHD571YHHILHHHHH581QNHHPHSHSQ591RYSREELKDA
601-650601GIATLAWMVI611MGDGLHNFSD621GLAIGAAFTE631GLSSGLSTSV641AVFCHELPHE
651-700651LGDFAVLLKA661GMTVKQAVLY671NALSAMLAYL681GMATGIFIGH691YAENVSMWIF
701-750701ALTAGLFMYV711ALVDMVPEML721HNDASDHGCS731RWGYFFLQNA741GILLGFGIML
751-765751LISIFEHKIV761FRINF
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
153 SWISSPALM DBPTM CYSMODDB -
Forebrain (28680068)
Brain (35358180)
Deep-Palm: 0.64
273 - - -
Deep-Palm: 0.06
300 - - -
Deep-Palm: 0.49
312 - - -
GPS-Palm: 0.92
Deep-Palm: 0.78
546 - - -
Deep-Palm: 0.02
550 - - -
Deep-Palm: 0.03
644 - - -
Deep-Palm: 0.92
729 - - -
Deep-Palm: 0.40
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
Testis
Specificity: 0.091
2/2 (100.0%)
1
Liver
Specificity: 0.045
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
19
Brain tissue (Mass)
Specificity: 0.864
19/56 (33.9%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine