Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8C172 | Cers6 | Ceramide synthase 6 (CerS6) (EC … | Mus musculus (Mouse) | 384 aa |
Protein Details: Q8C172 (Cers6)
Protein Information
| Accession | Q8C172 |
|---|---|
| Protein Names | Ceramide synthase 6 (CerS6) (EC 2.3.1.-) (LAG1 longevity assurance homolog 6) (Sphingoid base N-palmitoyltransferase CERS6) (EC 2.3.1.291) |
| Gene Symbol | Cers6 |
| Organism | Mus musculus (Mouse) |
| Length | 384 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29217618 37925639 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAGILAWFWN11ERFWLPHNVT21WADLKNTEEA31TFPQAEDLYL41AFPLAFCIFM
51-10051VRLIFERFIA61KPCAIALNIQ71ANGPQTAQPN81AILEKVFTAI91TKHPDEKRLE
101-150101GLSKQLDWDV111RSIQRWFRQR121RNQEKPSTLT131RFCESMWRFS141FYLYVFSYGV
151-200151RFLKQTPWLW161NTRHCWYNYP171YQPLTADLHY181YYILELSFYW191SLMVSQFTDI
201-250201KRKDFGIMFL211HHLATIFLIT221FSYVNNMARV231GTLVLCLHDS241ADALLEAAKM
251-300251ANYAKFQKMC261DLLFVMFAVV271FITTRLGIFP281LWVLNTTLFE291SWEIVGPYPS
301-350301WWVFNLLLLL311LQGLNCFWSY321LIVKIACKTV331SKGKVSKDDR341SDIESSSDDE
351-384351DSEPPGKKPH361SSTTTNGTSG371TNGYLLTGPC381SVDD
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 47 | - | - | - |
Deep-Palm: 0.79
|
|
| 63 | - | - | - |
Deep-Palm: 0.69
|
|
| 133 | - | - | - |
Deep-Palm: 0.18
|
|
| 165 | - | - | - |
Deep-Palm: 0.04
|
|
| 236 | SWISSPALM DBPTM CYSMODDB | TLC domain |
Forebrain
(28680068)
| - |
Deep-Palm: 0.96
|
| 260 | - | - | - |
Deep-Palm: 0.26
|
|
| 316 | - | - | - |
Deep-Palm: 0.69
|
|
| 327 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.35
|
|
| 380 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
1
Raw 264.7
Specificity: 0.500
1/1 (100.0%)
1
Liver
Specificity: 0.500
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.