Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8C419 Gpr158 Metabotropic glycine receptor (mGlyR) (G-protein … Mus musculus (Mouse) 1200 aa

Protein Details: Q8C419 (Gpr158)

Protein Information
AccessionQ8C419
Protein NamesMetabotropic glycine receptor (mGlyR) (G-protein coupled receptor 158)
Gene SymbolGpr158
OrganismMus musculus (Mouse)
Length1200 aa
IsoformsNo isoforms
Related PMIDs 29733200 34200797 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MGAMAYSLLF11CLLLAHLGLG21EVGASLDPPG31RPDSPRERTP41RGKQHGQQLP
51-10051RASAPDPSIP61WSRSTDGTIL71AQKLAEEVPV81DVASYLYTGD91FHQLKRANCS
101-150101GRYELAGLPG111KSPSLASSHP121SLHGALDTLT131HATNFLNMML141QSNKSREQTV
151-200151QDDLQWYQAL161VRSLLEGEPS171ISRAAITFST181ESLSTPAPQV191FLQATREESR
201-250201ILLQDLSSSA211HHLANATLET221EWFHGLRRKW231RPHLHRRGSN241QGPRGLGHSW
251-300251RRRDGLGGDR261SHVKWSPPYL271ECENGSYKPG281WLVTLSAAFY291GLQPNLVPEF
301-350301RGVMKVDISL311QKVDIDQCSS321DGWFSGTHKC331HLNNSECMPI341KGLGFVLGAY
351-400351QCICKAGFYH361PRVFSVNNFQ371RRGPDHHFSG381STKDVSEETH391VCLPCREGCP
401-450401FCADDRPCFV411QEDKYLRLAI421ISFQALCMLL431DFVSMLVVYH441FRKAKSIRAS
451-500451GLILLETILF461GSLLLYFPVV471ILYFEPSTFR481CILLRWARLL491GFATVYGTVT
501-550501LKLHRVLKVF511LSRTAQRIPY521MTGGRVMRML531AVIVLVVFWF541LVGWTSSMCQ
551-600551NLERDILLVG561QGQTSDHLTF571NMCLIDRWDY581MTAVAEFLFL591LWGIYLCYAV
601-650601RTVPSAFHEP611RYMAVAVHNE621LIITAIFHTI631RFVLASRLQP641DWMLMLYFAH
651-700651AHLTVTVTIG661LLLIPKFSHS671SNNPRDDIAT681EAYEDELDMG691RSGSYLNSSI
701-750701NSAWSEHSLD711PEDIRDELKK721LYAQLEIYKR731KKMITNNPHL741QKKRCSKKGL
751-800751GRSIMRRITE761IPETVSRQCS771KEDKEGTDHS781AAKGTGLVRK791NPTESSGNTG
801-850801RPKEESLKNR811VFSLKKSHST821YDHVRDQTVE831SSSLPMESQE841EEATENSTLE
851-900851SLSSKKLTQK861LKEDSEAEST871ESVPLVCKSA881SAHNLSSEKK891PGHPRTSMLQ
901-950901KSLSVIASAK911EKTLGLAGKT921QTLVMEDRAK931SQKPKDRETI941RKYSNSDNVE
951-1000951TIPNSGHMEE961PRKPQKSGIM971KQQRVSLPTA981NPDVSSGITQ991IKDNFDIGEV
1001-10501001CPWEVYDLTP1011GPMPSEPKAQ1021KHVSIAASEV1031EQNPASFLKE1041KSYHKSKATE
1051-11001051GLYQANHKSI1061DKTEVCPWEI1071HSQSLLEDEN1081RLISKTPVLP1091GRAREENGSQ
1101-11501101LYTTNMCAGQ1111YEELPHKVVA1121PKVENENLNQ1131MGDQEKQTSS1141SVDIIPGSCN
1151-12001151SSNNSHQPLT1161SRAEVCPWEF1171EPLEQPNAER1181SVTLPASSAL1191SANKIPGPQK
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
11 - - -
Deep-Palm: 0.39
99 - - -
Deep-Palm: 0.95
272 - - -
Deep-Palm: 0.63
318 - -
Brain (35358180)
Deep-Palm: 0.04
330 - - -
Deep-Palm: 0.03
337 - - -
Deep-Palm: 0.09
352 - -
Brain (35358180)
Deep-Palm: 0.44
354 SWISSPALM DBPTM CYSMODDB GPR158/179 extracellular domain
Forebrain (28680068)
Brain (35358180)
Deep-Palm: 0.60
392 - -
Brain (35358180)
Deep-Palm: 0.25
395 - -
Brain (35358180)
Deep-Palm: 0.17
399 - -
Brain (35358180)
Deep-Palm: 0.16
402 - -
Brain (35358180)
Deep-Palm: 0.14
408 SWISSPALM DBPTM CYSMODDB -
Forebrain (28680068)
Brain (35358180)
Deep-Palm: 0.61
427 - - -
Deep-Palm: 0.59
481 - - -
Deep-Palm: 0.81
549 - - -
Deep-Palm: 0.83
573 - - -
Deep-Palm: 0.16
597 - - -
Deep-Palm: 0.84
745 - - -
Deep-Palm: 0.89
769 - - -
Deep-Palm: 0.85
877 -
brain (39008777)
Brain (35358180)
Deep-Palm: 0.94
1001 - -
Brain (35358180)
Deep-Palm: 0.22
1066 -
brain (39008777)
Brain (35358180)
Deep-Palm: 0.60
1107 - - -
Deep-Palm: 0.84
1149 -
Brain (34200797)
-
Deep-Palm: 0.42
1166 -
brain (39008777)
Brain (35358180)
Deep-Palm: 0.45
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
Brain
Specificity: 0.100
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
27
Brain tissue (Mass)
Specificity: 0.900
27/56 (48.2%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine