Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8CC86 Naprt Nicotinate phosphoribosyltransferase (NAPRTase) (EC 6.3.4.21) … Mus musculus (Mouse) 538 aa

Protein Details: Q8CC86 (Naprt)

Protein Information
AccessionQ8CC86
Protein NamesNicotinate phosphoribosyltransferase (NAPRTase) (EC 6.3.4.21) (Nicotinate phosphoribosyltransferase domain-containing protein 1)
Gene SymbolNaprt
OrganismMus musculus (Mouse)
Length538 aa
IsoformsNo isoforms
Related PMIDs 28526873 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MEMELDSEGR11MVVRPLLTDL21YQATMALGYW31RAGRACEAAE41FELFFRHCPF
51-10051GGSFALSAGL61QDCMRFLRAF71RLRDADVQFL81ASVLPPDTDP91AFFEHLRALD
101-150101CSGVTVRALP111EGSLAFPGVP121LLQVSGPLLL131VQLLETPLLC141LVSYASLVAT
151-200151NAARLRLIAG161PDKKLLEMGL171RRAQGPDGGF181TASIYSYLGG191FDSSSNTLAG
201-250201QLRGVPVAGT211LAHSFVTSFS221GSEVPPDPML231APASSEGPTV241DLPARVNLWL
251-300251KRVCLYLGLE261EQEPHPGERA271AFVAYALAFP281RAFQGLLDSY291SVRRSGLPNF
301-350301LAVALALGEL311GYRAVGVRLD321SGDLLQQAKE331IRGIFRTAGA341QFQMPWLESV
351-400351PIAVSNNIDE361SELMRLAQKG371SEVNVIGIGT381SVVTCPKQPS391MGCVYKLVSV
401-450401GGQPRIKLTE411DPEKQTLPGS421KAAFRFLGPD431GSLLLDLLQL441AEEPPPKAGQ
451-500451ELRVWPRGTQ461EPCTVKPAQV471EPLLRLYLQQ481GQLCEPLPSL491DESRRFAQQS
501-538501LSLLRPAHKQ511LQSPAVYPVA521LSEKLRALVD531SLSARGPL
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
36 Nicotinate phosphoribosyltransferase, N-terminal domain Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate phosphoribosyltransferase family nicotinate phosphoribosyltransferase - -
Deep-Palm: 0.65
48 Nicotinate phosphoribosyltransferase, N-terminal domain Nicotinate phosphoribosyltransferase family Nicotinate/Quinolinate PRTase N-terminal domain-like nicotinate phosphoribosyltransferase - -
Deep-Palm: 0.92
63 - - -
GPS-Palm: 0.96
Deep-Palm: 0.92
101 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
-
Deep-Palm: 0.98
140 - - -
Deep-Palm: 0.98
254 - - -
GPS-Palm: 0.93
Deep-Palm: 0.97
385 - - -
Deep-Palm: 0.90
393 - - -
Deep-Palm: 0.97
463 SWISSPALM DBPTM CYSMODDB Nicotinate phosphoribosyltransferase C-terminal domain
Liver (28526873)
-
Deep-Palm: 0.97
484 SWISSPALM DBPTM CYSMODDB Nicotinate phosphoribosyltransferase C-terminal domain
Liver (28526873)
-
GPS-Palm: 0.89
Deep-Palm: 0.98
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Liver
Specificity: 1.000
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine