Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8CFA2 Amt Aminomethyltransferase, mitochondrial (EC 2.1.2.10) (Glycine … Mus musculus (Mouse) 403 aa

Protein Details: Q8CFA2 (Amt)

Protein Information
AccessionQ8CFA2
Protein NamesAminomethyltransferase, mitochondrial (EC 2.1.2.10) (Glycine cleavage system T protein) (GCVT)
Gene SymbolAmt
OrganismMus musculus (Mouse)
Length403 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MHRIVSVVAP11LGFRLQAQPL21VQSRPLSSVQ31DVLRRTPLYD41FHLAHGGKMV
51-10051AFAGWSLPVQ61YRDSHVDSHL71HTRRHCSLFD81VSHMLQTKIF91GCDRVKLLES
101-150101VVVGDIAELR111PNQGTLSLFT121NEAGGILDDL131IVSNTSEGHL141YVVSNAGCRD
151-200151KDLALMQDKV161KEFQNRGLDV171GLEVVENALL181ALQGPTATQV191LQAGVTDDMK
201-250201KLPFMTSAVM211EVFGVSGCRV221TRCGYTGEDG231VEISVPATGA241VHLATTLLKN
251-300251PEVKLAGLAA261RDSLRLEAGL271CLYGNDIDEH281TTPVEGSLSW291TLGKRRRIAM
301-350301DFPGAKIIVP311QLKGEVQRRR321VGLICEGAPV331RAHSPILNTE341GTVIGTVTSG
351-400351CPSPSLKKNV361AMGYVPFKYS371RPGTQLLVEV381RRKQQMTVVS391KMPFVPTNYY
401-403401TLK
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
76 - - -
Deep-Palm: 0.11
92 - - -
Deep-Palm: 0.97
148 - - -
Deep-Palm: 0.92
218 - - -
Deep-Palm: 0.87
223 - - -
Deep-Palm: 0.91
271 - - -
Deep-Palm: 0.98
325 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
-
GPS-Palm: 0.94
Deep-Palm: 0.97
351 SWISSPALM DBPTM CYSMODDB Glycine cleavage T-protein C-terminal barrel domain
Liver (28526873)
-
GPS-Palm: 0.91
Deep-Palm: 0.88
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
5
Liver
Specificity: 1.000
5/5 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine