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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8CG76 Akr7a2 Aflatoxin B1 aldehyde reductase member … Mus musculus (Mouse) 367 aa

Protein Details: Q8CG76 (Akr7a2)

Protein Information
AccessionQ8CG76
Protein NamesAflatoxin B1 aldehyde reductase member 2 (EC 1.1.1.n11) (Succinic semialdehyde reductase) (SSA reductase)
Gene SymbolAkr7a2
OrganismMus musculus (Mouse)
Length367 aa
IsoformsNo isoforms
Related PMIDs 28526873 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MLRAASRAVG11RAAVRSAQRS21GTSVGRPLAM31SRPPPPRAAS41GAPLRPATVL
51-10051GTMEMGRRMD61ASASAASVRA71FLERGHSELD81TAFMYCDGQS91ENILGGLGLG
101-150101LGSGDCTVKI111ATKANPWEGK121SLKPDSIRSQ131LETSLKRLQC141PRVDLFYLHA
151-200151PDHSTPVEET161LRACHQLHQE171GKFVELGLSN181YASWEVAEIC191TLCKSNGWIL
201-250201PTVYQGMYNA211TTRQVEAELL221PCLRHFGLRF231YAYNPLAGGL241LTGKYKYEDK
251-300251DGKQPVGRFF261GNNWAETYRN271RFWKEHHFEA281IALVEKALQT291TYGTNAPRMT
301-350301SAALRWMYHH311SQLQGTRGDA321VILGMSSLEQ331LEQNLAATEE341GPLEPAVVEA
351-367351FDQAWNMVAH361ECPNYFR
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
86 - - -
Deep-Palm: 0.96
106 - - -
GPS-Palm: 0.89
Deep-Palm: 0.98
140 - - -
Deep-Palm: 0.94
164 - - -
Deep-Palm: 0.92
190 - - -
Deep-Palm: 0.60
193 - - -
Deep-Palm: 0.18
222 SWISSPALM DBPTM CYSMODDB Aldo/keto reductase family
Liver (28526873)
Brain (35358180)
GPS-Palm: 0.92
Deep-Palm: 0.96
362 - - -
Deep-Palm: 0.03
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
Liver
Specificity: 0.444
4/4 (100.0%)
2
Testis
Specificity: 0.222
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
Brain tissue (Mass)
Specificity: 0.333
3/56 (5.4%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine