Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8CHW4 Eif2b5 Translation initiation factor eIF2B subunit … Mus musculus (Mouse) 717 aa

Protein Details: Q8CHW4 (Eif2b5)

Protein Information
AccessionQ8CHW4
Protein NamesTranslation initiation factor eIF2B subunit epsilon (eIF2B GDP-GTP exchange factor subunit epsilon)
Gene SymbolEif2b5
OrganismMus musculus (Mouse)
Length717 aa
IsoformsNo isoforms
Related PMIDs 28526873 35477839 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAATAAVPGA11AAGRASKRGG21GGSGGGGTQG31AEEEPPPPLQ41AVLVADSFNR
51-10051RFFPISKDQP61RVLLPLANVA71LIDYTLEFLT81ATGVQETFVF91CCWKAAQIKE
101-150101HLQKSKWCHP111TSPNVVRIIT121SELYRSLGDV131LRDVDAKALV141RSDFLLIYGD
151-200151VISNINICRA161LEEHRLRRKL171EKNVSVMTMV181FKESSPSHPT191RCHEDNVVMA
201-250201VDSATNRVLH211FQKTQGLRRF221SFPLSLFQGS231GDGVEIRYDL241LDCHISICSP
251-300251QVAQLFTDNF261DYQTRDDFVR271GILMNEEVLG281NQIHLHVTTR291EYGARVSNLH
301-350301MYSAVCADVI311RRWVYPLTPE321VNFTDSTTQS331YTHSRHNIYR341GPEVSLGHGS
351-400351VLEENVLLGA361GTVIGSNCSI371TNSVIGPNCH381IGDNVVLDQA391YLWQGVRVAA
401-450401GAQIHQSLLC411DRAEVKERVK421LKPYCVLTSQ431VVVGPDITLP441EGSVISLHPP
451-500451DAEEDEDDGQ461FSDDSGADQE471KEKVKLKGYN481PAEVGLEGQG491YLWKAEGVNS
501-550501KEDEELRQSL511WGLMIKTEEE521SETESEGSVD531PEELDSRAGS541PQLDDIRVFQ
551-600551NEVLGTLQRG561REENISCENL571VLEINSLKHA581YNISLKEVMQ591VLTLVVLEFP
601-650601LQQVDGLLDP611NRYCALLLPL621LKAWSPVLRN631YIKRAADHLE641ALAAIEDFFL
651-700651EHETLVTSMA661KVLMAFYQLE671ILAEETILSW681FSQRDTTDEG691QQLRKNQQLQ
701-717701RFIQWLREAE711EESSEDD
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
91 - - -
Deep-Palm: 0.89
92 - - -
Deep-Palm: 0.43
108 - - -
Deep-Palm: 0.71
158 - - -
Deep-Palm: 0.88
192 - - -
Deep-Palm: 0.12
243 - - -
Deep-Palm: 0.59
248 - - -
Deep-Palm: 0.24
306 - - -
Deep-Palm: 0.80
368 - - -
Deep-Palm: 0.79
379 - - -
Deep-Palm: 0.14
410 - - -
Deep-Palm: 0.97
425 - - -
Deep-Palm: 0.97
567 - - -
Deep-Palm: 0.94
614 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
-
GPS-Palm: 0.93
Deep-Palm: 0.98
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
Liver
Specificity: 0.667
4/4 (100.0%)
2
Testis
Specificity: 0.333
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine