Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8CIM3 D2hgdh D-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.39) Mus musculus (Mouse) 535 aa

Protein Details: Q8CIM3 (D2hgdh)

Protein Information
AccessionQ8CIM3
Protein NamesD-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.39)
Gene SymbolD2hgdh
OrganismMus musculus (Mouse)
Length535 aa
IsoformsNo isoforms
Related PMIDs 28526873
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MVLPLVSRWS11ARVLWASPGW21RRTYTQRACV31GLKRLGCPRG41VYSPLAHRAY
51-10051SVVAGGPEVT61LTPERYPVQR71LPFSTVSEED81LAAFECIIPG91RVITDPEQLQ
101-150101TCNVDWLKTV111RGCSKVLLRP121QTSEEVSQIL131RHCYKRNLAV141NPQGGNTGMV
151-200151GGSVPVFDEV161ILSTALMNQV171ISFHDVSGIL181VCQAGCVLEE191LSRYVQERDF
201-250201IMPLDLGAKG211SCHIGGNVAT221NAGGLRFLRY231GSLRGTVLGL241EVVLADGTIL
251-300251NCLTSLRKDN261TGYDLKQMFI271GSEGTLGVIT281AVSIVCPPRP291KAVNVAFLGC
301-350301PGFAEVLQTF311RTCRGMLGEI321LSAFEFMDTE331CMQLVGQHLQ341LTNPVQESPF
351-400351YVLVETSGSS361AGHDAEKLTN371VLEQVLNSGL381VTDGTMATDQ391RKVQMLWALR
401-450401ERITEALSRD411GYVFKYDLSL421PVERLYDLVI431DLRTRLGPRA441KHVVGYGHLG
451-500451DGNLHLNVTA461EAFSRELLGA471LEPYVYAWTA481EQRGSVSAEH491GLGFKKKDVL
501-535501GYSKPPVAVT511LMQQLKAMLD521PEGILNPYKT531LPAQA
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
29 - - -
Deep-Palm: 0.93
37 - - -
Deep-Palm: 0.94
86 - - -
Deep-Palm: 0.96
102 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
-
Deep-Palm: 0.79
113 - - -
Deep-Palm: 0.95
133 - - -
Deep-Palm: 0.89
182 - - -
Deep-Palm: 0.80
186 - - -
Deep-Palm: 0.85
212 - - -
Deep-Palm: 0.96
252 - - -
GPS-Palm: 0.92
Deep-Palm: 0.98
286 - - -
Deep-Palm: 0.97
300 - - -
GPS-Palm: 0.92
Deep-Palm: 0.84
313 - - -
Deep-Palm: 0.89
331 - - -
Deep-Palm: 0.23
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
Liver
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine