Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8IUW5 | RELL1 | RELT-like protein 1 | Homo sapiens (Human) | 271 aa |
Protein Details: Q8IUW5 (RELL1)
Protein Information
| Accession | Q8IUW5 |
|---|---|
| Protein Names | RELT-like protein 1 |
| Gene Symbol | RELL1 |
| Organism | Homo sapiens (Human) |
| Length | 271 aa |
| Isoforms | No isoforms |
| Related PMIDs | 24357059 26111759 31251020 31382980 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAPRALPGSA11VLAAAVFVGG21AVSSPLVAPD31NGSSRTLHSR41TETTPSPSND
51-10051TGNGHPEYIA61YALVPVFFIM71GLFGVLICHL81LKKKGYRCTT91EAEQDIEEEK
101-150101VEKIELNDSV111NENSDTVGQI121VHYIMKNEAN131ADVLKAMVAD141NSLYDPESPV
151-200151TPSTPGSPPV161SPGPLSPGGT171PGKHVCGHHL181HTVGGVVERD191VCHRCRHKRW
201-250201HFIKPTNKSR211ESRPRRQGEV221TVLSVGRFRV231TKVEHKSNQK241ERRSLMSVSG
251-271251AETVNGEVPA261TPVKRERSGT271E
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 78 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.92
|
|
| 88 | SWISSPALM DBPTM CYSMODDB | Tumour necrosis factor receptor superfamily member 19 | - |
LNCaP
(31251020)
|
GPS-Palm: 0.66
Deep-Palm: 0.53
|
| 176 | - | - | - |
Deep-Palm: 0.81
|
|
| 192 | - | - | - |
Deep-Palm: 0.04
|
|
| 195 | - | - | - |
Deep-Palm: 0.14
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.333
3
LNCaP
Specificity: 0.300
3/3 (100.0%)
2
Primary T cell
Specificity: 0.200
2/2 (100.0%)
2
Jurkat T cell
Specificity: 0.200
2/2 (100.0%)
1
U937 cell
Specificity: 0.100
1/1 (100.0%)
1
HUVECs
Specificity: 0.100
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 0.100
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 87 | R → C | 0.002545 | SNP | Missense Mutation | GBM |