Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8IWE4 | DCUN1D3 | DCN1-like protein 3 (DCNL3) (DCUN1 … | Homo sapiens (Human) | 304 aa |
Protein Details: Q8IWE4 (DCUN1D3)
Protein Information
| Accession | Q8IWE4 |
|---|---|
| Protein Names | DCN1-like protein 3 (DCNL3) (DCUN1 domain-containing protein 3) (Defective in cullin neddylation protein 1-like protein 3) (Squamous cell carcinoma-related oncogene 3) |
| Gene Symbol | DCUN1D3 |
| Organism | Homo sapiens (Human) |
| Length | 304 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26111759 31251020 32944167 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGQCVTKCKN11PSSTLGSKNG21DREPSNKSHS31RRGAGHREEQ41VPPCGKPGGD
51-10051ILVNGTKKAE61AATEACQLPT71SSGDAGRESK81SNAEESSLQR91LEELFRRYKD
101-150101EREDAILEEG111MERFCNDLCV121DPTEFRVLLL131AWKFQAATMC141KFTRKEFFDG
151-200151CKAISADSID161GICARFPSLL171TEAKQEDKFK181DLYRFTFQFG191LDSEEGQRSL
201-250201HREIAIALWK211LVFTQNNPPV221LDQWLNFLTE231NPSGIKGISR241DTWNMFLNFT
251-300251QVIGPDLSNY261SEDEAWPSLF271DTFVEWEMER281RKREGEGRGA291LSSGPEGLCP
301-304301EEQT
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 4 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.02
|
| 8 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.02
|
| 44 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.95
|
|
| 66 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.96
|
|
| 115 | - | - | - |
Deep-Palm: 0.84
|
|
| 119 | - | - | - |
Deep-Palm: 0.65
|
|
| 140 | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.83
|
|
| 151 | - | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.46
|
|
| 163 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.96
|
|
| 299 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.17
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.333
4
PC3
Specificity: 0.308
4/4 (100.0%)
3
Primary T cell
Specificity: 0.231
3/3 (100.0%)
3
Jurkat T cell
Specificity: 0.231
3/3 (100.0%)
2
LNCaP
Specificity: 0.154
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 0.077
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 147 | F → C | 0.001969 | SNP | Missense Mutation | LGG |
| 183 | Y → C | 0.002427 | SNP | Missense Mutation | BLCA |