Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8IWE4 | DCUN1D3; SCCRO3 | DCN1-like protein 3 (DCNL3) (DCUN1 … | Homo sapiens (Human) | 304 aa |
Protein Details: Q8IWE4 (DCUN1D3)
Protein Information
| Accession | Q8IWE4 |
|---|---|
| Protein Names | DCN1-like protein 3 (DCNL3) (DCUN1 domain-containing protein 3) (Defective in cullin neddylation protein 1-like protein 3) (Squamous cell carcinoma-related oncogene 3) |
| Gene Symbol | DCUN1D3; SCCRO3 |
| Organism | Homo sapiens (Human) |
| Length | 304 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 26111759 31251020 32944167 |
| Database Sources | dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.520
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
13
LNCaP cells
Specificity: 0.520
13/46 (28.3%)
4
PC3 cells
Specificity: 0.160
4/4 (100.0%)
3
Jurkat T cells
Specificity: 0.120
3/25 (12.0%)
3
T cells
Specificity: 0.120
3/4 (75.0%)
2
DU145 cells
Specificity: 0.080
2/2 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGQCVTKCKN11PSSTLGSKNG21DREPSNKSHS31RRGAGHREEQ41VPPCGKPGGD
51-10051ILVNGTKKAE61AATEACQLPT71SSGDAGRESK81SNAEESSLQR91LEELFRRYKD
101-150101EREDAILEEG111MERFCNDLCV121DPTEFRVLLL131AWKFQAATMC141KFTRKEFFDG
151-200151CKAISADSID161GICARFPSLL171TEAKQEDKFK181DLYRFTFQFG191LDSEEGQRSL
201-250201HREIAIALWK211LVFTQNNPPV221LDQWLNFLTE231NPSGIKGISR241DTWNMFLNFT
251-300251QVIGPDLSNY261SEDEAWPSLF271DTFVEWEMER281RKREGEGRGA291LSSGPEGLCP
301-304301EEQT
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 4 | DBPTM SWISSPALM Prediction (High) | - | - |
| 8 | DBPTM SWISSPALM Prediction (High) | - | - |
| 44 | Prediction (Low) | - | - |
| 66 | Prediction (Low) | - | - |
| 140 | Prediction (Medium) | - | - |
| 151 | Prediction (Medium) | - | - |
| 163 | Prediction (Low) | - | - |
| 299 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 147 | F → C | 0.001969 | SNP | Missense Mutation | LGG |
| 183 | Y → C | 0.002427 | SNP | Missense Mutation | BLCA |