Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8JZQ2 Afg3l2 Mitochondrial inner membrane m-AAA protease … Mus musculus (Mouse) 802 aa

Protein Details: Q8JZQ2 (Afg3l2)

Protein Information
Accession Q8JZQ2
Protein Names Mitochondrial inner membrane m-AAA protease component AFG3L2 (EC 3.4.24.-) (EC 3.6.-.-) (AFG3-like protein 2)
Gene Symbol Afg3l2
Organism Mus musculus (Mouse)
Length 802 aa
Isoforms No isoforms
Related PMIDs 28526873 28680068 29733200 34200797 34884899 35358180 35477839 37925639
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.543
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
19
Liver tissue
Specificity: 0.543
19/19 (100.0%)
8
Brain tissue
Specificity: 0.229
8/12 (66.7%)
6
Liver membrane
Specificity: 0.171
6/6 (100.0%)
2
Testis
Specificity: 0.057
2/2 (100.0%)
0
Macrophage Raw 264.7
Specificity: 0.000
0/2 (0.0%)
0
Neural Stem Cells
Specificity: 0.000
0/3 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAHRCLLLWS11RGGCRRGLPP21LLVPRGCLGP31DRRPCLRTLY41QYATVQTASS
51-10051RRSLLRDVIA61AYQRFCSRPP71KGFEKYFPNG81KNGKKASEPK91EAVGEKKEPQ
101-150101PSGPQPSGGA111GGGGGKRRGK121KEDSHWWSRF131QKGDFPWDDK141DFRMYFLWTA
151-200151LFWGGVMIYF161VFKSSGREIT171WKDFVNNYLS181KGVVDRLEVV191NKRFVRVTFT
201-250201PGKTPVDGQY211VWFNIGSVDT221FERNLETLQQ231ELGIEGENRV241PVVYIAESDG
251-300251SFLLSMLPTV261LIIAFLLYTI271RRGPAGIGRT281GRGMGGLFSV291GETTAKVLKD
301-350301EIDVKFKDVA311GCEEAKLEIM321EFVNFLKNPK331QYQDLGAKIP341KGAILTGPPG
351-400351TGKTLLAKAT361AGEANVPFIT371VSGSEFLEMF381VGVGPARVRD391LFALARKNAP
401-450401CILFIDEIDA411VGRKRGRGNF421GGQSEQENTL431NQLLVEMDGF441NTTTNVVILA
451-500451GTNRPDILDP461ALLRPGRFDR471QIFIGPPDIK481GRASIFKVHL491RPLKLDSALE
501-550501KDKLARKLAS511LTPGFSGADV521ANVCNEAALI531AARHLSDAIN541EKHFEQAIER
551-600551VIGGLEKKTQ561VLQPEEKKTV571AYHEAGHAVA581GWYLEHADPL591LKVSIIPRGK
601-650601GLGYAQYLPK611EQYLYTKEQL621LDRMCMTLGG631RVSEEIFFGR641ITTGAQDDLR
651-700651KVTQSAYAQI661VQFGMNEKVG671QISFDLPRQG681DMVLEKPYSE691ATARMIDDEV
701-750701RILISDAYRR711TVALLTEKKA721DVEKVALLLL731EKEVLDKNDM741VQLLGPRPFT
751-800751EKSTYEEFVE761GTGSLDEDTS771LPEGLQDWNK781EREKEEKKEK791EKEEPLNEKV
801-802801VS
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
5 Prediction (High) - -
27 Prediction (High) - -
66 Prediction (High) - -
401 Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) ATPase family associated with various cellular activities (AAA) 28526873
524 Experimental CYSMODDB SWISSPALM DBPTM AAA+ lid domain 28680068
Conservation Scores
PhyloP
PhastCons