Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8JZQ2 | Afg3l2 | Mitochondrial inner membrane m-AAA protease … | Mus musculus (Mouse) | 802 aa |
Protein Details: Q8JZQ2 (Afg3l2)
Protein Information
| Accession | Q8JZQ2 |
|---|---|
| Protein Names | Mitochondrial inner membrane m-AAA protease component AFG3L2 (EC 3.4.24.-) (EC 3.6.-.-) (AFG3-like protein 2) |
| Gene Symbol | Afg3l2 |
| Organism | Mus musculus (Mouse) |
| Length | 802 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29733200 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAHRCLLLWS11RGGCRRGLPP21LLVPRGCLGP31DRRPCLRTLY41QYATVQTASS
51-10051RRSLLRDVIA61AYQRFCSRPP71KGFEKYFPNG81KNGKKASEPK91EAVGEKKEPQ
101-150101PSGPQPSGGA111GGGGGKRRGK121KEDSHWWSRF131QKGDFPWDDK141DFRMYFLWTA
151-200151LFWGGVMIYF161VFKSSGREIT171WKDFVNNYLS181KGVVDRLEVV191NKRFVRVTFT
201-250201PGKTPVDGQY211VWFNIGSVDT221FERNLETLQQ231ELGIEGENRV241PVVYIAESDG
251-300251SFLLSMLPTV261LIIAFLLYTI271RRGPAGIGRT281GRGMGGLFSV291GETTAKVLKD
301-350301EIDVKFKDVA311GCEEAKLEIM321EFVNFLKNPK331QYQDLGAKIP341KGAILTGPPG
351-400351TGKTLLAKAT361AGEANVPFIT371VSGSEFLEMF381VGVGPARVRD391LFALARKNAP
401-450401CILFIDEIDA411VGRKRGRGNF421GGQSEQENTL431NQLLVEMDGF441NTTTNVVILA
451-500451GTNRPDILDP461ALLRPGRFDR471QIFIGPPDIK481GRASIFKVHL491RPLKLDSALE
501-550501KDKLARKLAS511LTPGFSGADV521ANVCNEAALI531AARHLSDAIN541EKHFEQAIER
551-600551VIGGLEKKTQ561VLQPEEKKTV571AYHEAGHAVA581GWYLEHADPL591LKVSIIPRGK
601-650601GLGYAQYLPK611EQYLYTKEQL621LDRMCMTLGG631RVSEEIFFGR641ITTGAQDDLR
651-700651KVTQSAYAQI661VQFGMNEKVG671QISFDLPRQG681DMVLEKPYSE691ATARMIDDEV
701-750701RILISDAYRR711TVALLTEKKA721DVEKVALLLL731EKEVLDKNDM741VQLLGPRPFT
751-800751EKSTYEEFVE761GTGSLDEDTS771LPEGLQDWNK781EREKEEKKEK791EKEEPLNEKV
801-802801VS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 5 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.05
|
|
| 14 | - | - | - |
Deep-Palm: 0.98
|
|
| 27 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.97
|
|
| 35 | - | - | - |
Deep-Palm: 0.95
|
|
| 66 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.95
|
|
| 312 | - | - | - |
Deep-Palm: 0.87
|
|
| 401 | SWISSPALM DBPTM CYSMODDB | ATPase family associated with various cellular activities (AAA) |
Liver
(28526873)
| - |
GPS-Palm: 0.95
Deep-Palm: 0.98
|
| 524 | SWISSPALM DBPTM CYSMODDB | AAA+ lid domain |
Forebrain
(28680068)
|
Brain
(35358180)
|
Deep-Palm: 0.97
|
| 625 | - | - | - |
Deep-Palm: 0.90
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
6
Liver
Specificity: 0.250
6/6 (100.0%)
4
Brain
Specificity: 0.167
4/4 (100.0%)
2
Testis
Specificity: 0.083
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
12
Brain tissue (Mass)
Specificity: 0.500
12/56 (21.4%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.