Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8K182 | C8a | Complement component C8 alpha chain … | Mus musculus (Mouse) | 587 aa |
Protein Details: Q8K182 (C8a)
Protein Information
| Accession | Q8K182 |
|---|---|
| Protein Names | Complement component C8 alpha chain (Complement component 8 subunit alpha) |
| Gene Symbol | C8a |
| Organism | Mus musculus (Mouse) |
| Length | 587 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 34884899 35477839 37925639 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MFVVAFFGLS11LVAWHPGVTA21QEKVNQRVTR31AVTPQAVSCQ41LSDWYKWTDC
51-10051FPCQDKKYRY61RSLLQPSKFG71GTICSGDIWD81EASCDSPTPC91LRQAQCGQDF
101-150101QCRETGRCLK111RHLVCNGDND121CLDGSDESDC131EDVRVTEDDC141HQYEPIPGSE
151-200151RAALGYNILT161QEEAQSVYDA171KYYGGQCETV181YNGDWRKLRY191DPTCERLYYG
201-250201EDEKYFRKPY211NFLKYHFEAL221ADTSISSEFY231DDANDLFFHI241KNGKSHSAGV
251-300251TVGVAPVKSP261VSIEVTGSGS271KASSFLNKLN281KYNEKRYGFM291RVSTKIQTAQ
301-350301FKMRRNNIVL311DEGMLQSLME321LPEQFNYGMY331AKFINDYGTH341YITSGTMGGI
351-400351YEYVMVLDKE361KMKTEGTTVD371EVQKCIGGGI381GIGIKDSTIE391GVGISGEFCE
401-450401NSGDGDRDIR411KKITGVEDII421SRVQGGSSVW431GSVLTHNSSA441ITYQSWGRSL
451-500451KYNPVVIDFE461MQPIYQLLRH471TNLGPLETKR481QNLRRALDQY491LMEFNACRCG
501-550501PCFNNGEPIL511DGTNCRCQCS521MGRQGLACER531TVIEGLKDFK541AAGHWSCWSS
551-587551WSECRGGSQE561RRRQCNNPPP571KNGGTPCLGR581NLQTQAC
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 39 | COMPLEMENT COMPONENT C6 | - | - |
Deep-Palm: 0.04
|
|
| 50 | COMPLEMENT COMPONENT C6 Thrombospondin type-1 (TSP1) repeat superfamily | - | - |
Deep-Palm: 0.05
|
|
| 53 | - | - | - |
Deep-Palm: 0.05
|
|
| 74 | - | - | - |
Deep-Palm: 0.85
|
|
| 84 | - | - | - |
Deep-Palm: 0.32
|
|
| 90 | - | - | - |
Deep-Palm: 0.20
|
|
| 96 | - | - | - |
Deep-Palm: 0.27
|
|
| 102 | - | - | - |
Deep-Palm: 0.13
|
|
| 108 | - | - | - |
Deep-Palm: 0.10
|
|
| 115 | - | - | - |
Deep-Palm: 0.10
|
|
| 121 | - | - | - |
Deep-Palm: 0.13
|
|
| 130 | - | - | - |
Deep-Palm: 0.03
|
|
| 140 | - | - | - |
Deep-Palm: 0.78
|
|
| 177 | - | - | - |
Deep-Palm: 0.22
|
|
| 194 | - | - | - |
Deep-Palm: 0.62
|
|
| 375 | - | - | - |
Deep-Palm: 0.77
|
|
| 399 | - | - | - |
Deep-Palm: 0.84
|
|
| 497 | SWISSPALM DBPTM CYSMODDB | Complement components C8A/B/C6 EGF-like domain |
Liver
(28526873)
| - |
Deep-Palm: 0.84
|
| 499 | - | - | - |
Deep-Palm: 0.18
|
|
| 502 | - | - | - |
Deep-Palm: 0.02
|
|
| 515 | - | - | - |
Deep-Palm: 0.04
|
|
| 517 | - | - | - |
Deep-Palm: 0.04
|
|
| 519 | - | - | - |
Deep-Palm: 0.13
|
|
| 528 | - | - | - |
Deep-Palm: 0.35
|
|
| 547 | - | - | - |
Deep-Palm: 0.22
|
|
| 554 | - | - | - |
Deep-Palm: 0.03
|
|
| 565 | - | - | - |
Deep-Palm: 0.08
|
|
| 577 | - | - | - |
Deep-Palm: 0.03
|
|
| 587 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.03
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.714
5
Liver
Specificity: 0.714
5/5 (100.0%)
2
Testis
Specificity: 0.286
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.