Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8N357 | SLC35F6 | Solute carrier family 35 member … | Homo sapiens (Human) | 371 aa |
Protein Details: Q8N357 (SLC35F6)
Protein Information
| Accession | Q8N357 |
|---|---|
| Protein Names | Solute carrier family 35 member F6 (ANT2-binding protein) (ANT2BP) (Transport and Golgi organization 9 homolog) |
| Gene Symbol | SLC35F6 |
| Organism | Homo sapiens (Human) |
| Length | 371 aa |
| Isoforms | No isoforms |
| Related PMIDs | 24357059 26111759 31251020 33636221 36430497 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAWTKYQLFL11AGLMLVTGSI21NTLSAKWADN31FMAEGCGGSK41EHSFQHPFLQ
51-10051AVGMFLGEFS61CLAAFYLLRC71RAAGQSDSSV81DPQQPFNPLL91FLPPALCDMT
101-150101GTSLMYVALN111MTSASSFQML121RGAVIIFTGL131FSVAFLGRRL141VLSQWLGILA
151-200151TIAGLVVVGL161ADLLSKHDSQ171HKLSEVITGD181LLIIMAQIIV191AIQMVLEEKF
201-250201VYKHNVHPLR211AVGTEGLFGF221VILSLLLVPM231YYIPAGSFSG241NPRGTLEDAL
251-300251DAFCQVGQQP261LIAVALLGNI271SSIAFFNFAG281ISVTKELSAT291TRMVLDSLRT
301-350301VVIWALSLAL311GWEAFHALQI321LGFLILLIGT331ALYNGLHRPL341LGRLSRGRPL
351-371351AEESEQERLL361GGTRTPINDA371S
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 36 | - | - | - |
Deep-Palm: 0.48
|
|
| 61 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.85
|
|
| 70 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.84
|
| 97 | - | - | - |
Deep-Palm: 0.56
|
|
| 254 | - | - | - |
GPS-Palm: 0.77
Deep-Palm: 0.94
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.273
3
LNCaP
Specificity: 0.273
3/3 (100.0%)
3
Primary T cell
Specificity: 0.273
3/3 (100.0%)
3
cerebral cortex
Specificity: 0.273
3/3 (100.0%)
1
heart
Specificity: 0.091
1/1 (100.0%)
1
HUVECs
Specificity: 0.091
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 243 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 299 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| ? | ? → ? | 0.001887 | SNP | Missense Mutation | UCEC |