Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8N6F7 | GCSAM | Germinal center-associated signaling and motility … | Homo sapiens (Human) | 178 aa |
Protein Details: Q8N6F7 (GCSAM)
Protein Information
| Accession | Q8N6F7 |
|---|---|
| Protein Names | Germinal center-associated signaling and motility protein (Germinal center B-cell-expressed transcript 2 protein) (Germinal center-associated lymphoma protein) (hGAL) |
| Gene Symbol | GCSAM |
| Organism | Homo sapiens (Human) |
| Length | 178 aa |
| Isoforms | No isoforms |
| Related PMIDs | 25914232 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGNSLLRENR11RQQNTQEMPW21NVRMQSPKQR31TSRCWDHHIA41EGCFCLPWKK
51-10051ILIFEKRQDS61QNENERMSST71PIQDNVDQTY81SEELCYTLIN91HRVLCTRPSG
101-150101NSAEEYYENV111PCKAERPRES121LGGTETEYSL131LHMPSTDPRH141ARSPEDEYEL
151-178151LMPHRISSHF161LQQPRPLMAP171SETQFSHL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 34 | - | - | - |
Deep-Palm: 0.06
|
|
| 43 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.25
|
|
| 45 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.25
|
|
| 85 | - | - | - |
Deep-Palm: 0.46
|
|
| 95 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.62
|
|
| 112 | - | - | - |
Deep-Palm: 0.86
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
CEM 174 cell
Specificity: 1.000
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 34 | C → S | 0.001764 | SNP | Missense Mutation | LUAD |
| 35 | W → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 85 | C → C | 0.001887 | SNP | Silent | UCEC |
| 165 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |