Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8N6M3 | FITM2 | Acyl-coenzyme A diphosphatase FITM2 (EC … | Homo sapiens (Human) | 262 aa |
Protein Details: Q8N6M3 (FITM2)
Protein Information
| Accession | Q8N6M3 |
|---|---|
| Protein Names | Acyl-coenzyme A diphosphatase FITM2 (EC 3.6.1.-) (Fat storage-inducing transmembrane protein 2) (Fat-inducing protein 2) |
| Gene Symbol | FITM2 |
| Organism | Homo sapiens (Human) |
| Length | 262 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 33636221 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MEHLERCEWL11LRGTLVRAAV21RRYLPWALVA31SMLAGSLLKE41LSPLPESYLS
51-10051NKRNVLNVYF61VKVAWAWTFC71LLLPFIALTN81YHLTGKAGLV91LRRLSTLLVG
101-150101TAIWYICTSI111FSNIEHYTGS121CYQSPALEGV131RKEHQSKQQC141HQEGGFWHGF
151-200151DISGHSFLLT161FCALMIVEEM171SVLHEVKTDR181SHCLHTAITT191LVVALGILTF
201-250201IWVLMFLCTA211VYFHNLSQKV221FGTLFGLLSW231YGTYGFWYPK241AFSPGLPPQS
251-262251CSLNLKQDSY261KK
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 7 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.09
|
|
| 70 | - | - | - |
Deep-Palm: 0.13
|
|
| 107 | - | - | - |
Deep-Palm: 0.51
|
|
| 121 | - | - | - |
Deep-Palm: 0.29
|
|
| 140 | - | - | - |
Deep-Palm: 0.29
|
|
| 162 | - | - | - |
Deep-Palm: 0.08
|
|
| 183 | - | - | - |
Deep-Palm: 0.90
|
|
| 208 | - | - | - |
Deep-Palm: 0.22
|
|
| 251 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.06
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
LNCaP
Specificity: 0.400
2/2 (100.0%)
1
heart
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
LNCaP cells (Mass)
Specificity: 0.400
2/4 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 70* | C → ? | 0.001887 | SNP | Nonsense Mutation | UCEC |