Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8N6M3 | FITM2; C20orf142; FIT2 | Acyl-coenzyme A diphosphatase FITM2 (EC … | Homo sapiens (Human) | 262 aa |
Protein Details: Q8N6M3 (FITM2)
Protein Information
| Accession | Q8N6M3 |
|---|---|
| Protein Names | Acyl-coenzyme A diphosphatase FITM2 (EC 3.6.1.-) (Fat storage-inducing transmembrane protein 2) (Fat-inducing protein 2) |
| Gene Symbol | FITM2; C20orf142; FIT2 |
| Organism | Homo sapiens (Human) |
| Length | 262 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 33636221 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.941
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
16
LNCaP cells
Specificity: 0.941
16/46 (34.8%)
1
Liver membrane
Specificity: 0.059
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MEHLERCEWL11LRGTLVRAAV21RRYLPWALVA31SMLAGSLLKE41LSPLPESYLS
51-10051NKRNVLNVYF61VKVAWAWTFC71LLLPFIALTN81YHLTGKAGLV91LRRLSTLLVG
101-150101TAIWYICTSI111FSNIEHYTGS121CYQSPALEGV131RKEHQSKQQC141HQEGGFWHGF
151-200151DISGHSFLLT161FCALMIVEEM171SVLHEVKTDR181SHCLHTAITT191LVVALGILTF
201-250201IWVLMFLCTA211VYFHNLSQKV221FGTLFGLLSW231YGTYGFWYPK241AFSPGLPPQS
251-262251CSLNLKQDSY261KK
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 7 | Prediction (Medium) | - | - |
| 251 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 70* | C → ? | 0.001887 | SNP | Nonsense Mutation | UCEC |