Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8N6S5 | ARL6IP6 | ADP-ribosylation factor-like protein 6-interacting protein … | Homo sapiens (Human) | 226 aa |
Protein Details: Q8N6S5 (ARL6IP6)
Protein Information
| Accession | Q8N6S5 |
|---|---|
| Protein Names | ADP-ribosylation factor-like protein 6-interacting protein 6 (ARL-6-interacting protein 6) (Aip-6) (Phosphonoformate immuno-associated protein 1) |
| Gene Symbol | ARL6IP6 |
| Organism | Homo sapiens (Human) |
| Length | 226 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 26111759 31251020 31382980 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSFAESGWRS11ALRRRGPGTP21GPVARPSYSS31FTQGDSWGEG41EVDEEEGCDQ
51-10051VARDLRAEFS61AGAWSEPRKR71SVLPPDGNGS81PVLPDKRNGI91FPAAAGSRAQ
101-150101PRRWPVQVLS111ILCSLLFAIL121LAFLLAIAYL131IVKELHAENL141KNEDDVDTGL
151-200151LGFWTLLIIS161LTAGFSCCSF171SWTVTYFDSF181EPGMFPPTPL191SPARFKKLTG
201-226201HSFHMGYSMA211ILNGIVAALT221VAWCLM
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 48 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
| - |
Deep-Palm: 0.94
|
| 113 | - | - | - |
Deep-Palm: 0.96
|
|
| 167 | - | - | - |
GPS-Palm: 0.67
Deep-Palm: 0.16
|
|
| 168 | - | - | - |
Deep-Palm: 0.20
|
|
| 224 | - | - | - |
GPS-Palm: 0.98
Deep-Palm: 0.01
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.417
5
Jurkat T cell
Specificity: 0.417
5/5 (100.0%)
3
LNCaP
Specificity: 0.250
3/3 (100.0%)
3
Primary T cell
Specificity: 0.250
3/3 (100.0%)
1
U937 cell
Specificity: 0.083
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 48 | C → Afs*83 | 0.001969 | DEL | Frame Shift Del | HNSC |
| 89 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 169 | S → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 172 | W → C | 0.001014 | SNP | Missense Mutation | BRCA |