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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8N6S5 ARL6IP6; PFAAP1 ADP-ribosylation factor-like protein 6-interacting protein … Homo sapiens (Human) 226 aa

Protein Details: Q8N6S5 (ARL6IP6)

Protein Information
Accession Q8N6S5
Protein Names ADP-ribosylation factor-like protein 6-interacting protein 6 (ARL-6-interacting protein 6) (Aip-6) (Phosphonoformate immuno-associated protein 1)
Gene Symbol ARL6IP6; PFAAP1
Organism Homo sapiens (Human)
Length 226 aa
Isoforms No isoforms
Related PMIDs 19801377 26111759 29575903 29733200 31251020 31382980
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.625
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
25
LNCaP cells
Specificity: 0.625
25/46 (54.3%)
4
Jurkat T cells
Specificity: 0.100
4/25 (16.0%)
4
T cells
Specificity: 0.100
4/4 (100.0%)
4
HAP1 cells
Specificity: 0.100
4/10 (40.0%)
2
DU145 cells
Specificity: 0.050
2/2 (100.0%)
1
U937 cells
Specificity: 0.025
1/1 (100.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSFAESGWRS11ALRRRGPGTP21GPVARPSYSS31FTQGDSWGEG41EVDEEEGCDQ
51-10051VARDLRAEFS61AGAWSEPRKR71SVLPPDGNGS81PVLPDKRNGI91FPAAAGSRAQ
101-150101PRRWPVQVLS111ILCSLLFAIL121LAFLLAIAYL131IVKELHAENL141KNEDDVDTGL
151-200151LGFWTLLIIS161LTAGFSCCSF171SWTVTYFDSF181EPGMFPPTPL191SPARFKKLTG
201-226201HSFHMGYSMA211ILNGIVAALT221VAWCLM
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
48 Experimental CYSMODDB SWISSPALM DBPTM - 29575903
167 Prediction (Low) - -
224 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
48 C → Afs*83 0.001969 DEL Frame Shift Del HNSC
89 G → C 0.001887 SNP Missense Mutation UCEC
169 S → C 0.001969 SNP Missense Mutation HNSC
172 W → C 0.001014 SNP Missense Mutation BRCA