Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8NCG7-2 | DAGLB | Diacylglycerol lipase-beta (DAGL-beta) (DGL-beta) (EC … | Homo sapiens (Human) | 391 aa |
Protein Details: Q8NCG7-2 (DAGLB)
Protein Information
| Accession | Q8NCG7-2 |
|---|---|
| Protein Names | Diacylglycerol lipase-beta (DAGL-beta) (DGL-beta) (EC 3.1.1.116) (KCCR13L) (PUFA-specific triacylglycerol lipase) (EC 3.1.1.3) (Sn1-specific diacylglycerol lipase beta) |
| Gene Symbol | DAGLB |
| Organism | Homo sapiens (Human) |
| Length | 391 aa |
| Isoforms | |
| Related PMIDs | 29575903 31251020 32651440 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MQFAAAAYGW11PLYIYRNPLT21GLCRIGGDCC31RSRTTDYDLV41GGDQLNCHFG
51-10051SILHTTGLQY61RDFIHVSFHD71KVYELPFLVA81LDHRKESVVV91AVRGTMSLQD
101-150101VLTDLSAESE111VLDVECEVQD121RLAHKGISQA131ARYVYQRLIN141DGILSQAFSI
151-200151APEYRLVIVG161HSLGGGAAAL171LATMLRAAYP181QVRCYAFSPP191RGLWSKALQE
201-250201YSQSFIVSLV211LGKDVIPRLS221VTNLEDLKRR231ILRVVAHCNK241PKYKILLHGL
251-300251WYELFGGNPN261NLPTELDGGD271QEVLTQPLLG281EQSLLTRWSP291AYSFSSDSPL
301-350301DSSPKYPPLY311PPGRIIHLQE321EGASGRFGCC331SAAHYSAKWS341HEAEFSKILI
351-391351GPKMLTDHMP361DILMRALDSV371VSDRAACVSC381PAQGVSSVDV391A
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 23 | - |
HeLa
(29575903)
| - | - | |
| 49 | - | - | - |
Deep-Palm: 0.95
|
|
| 71 | - | - | - |
Deep-Palm: 0.29
|
|
| 78 | - | - | - |
Deep-Palm: 0.51
|
|
| 86 | - | - | - |
Deep-Palm: 0.64
|
|
| 125 | - | - | - |
Deep-Palm: 0.88
|
|
| 201 | - | - | - |
Deep-Palm: 0.84
|
|
| 202 | - | - | - |
Deep-Palm: 0.73
|
|
| 203 | - | - | - |
Deep-Palm: 0.89
|
|
| 238 | - | - | - |
GPS-Palm: 0.91
|
|
| 260 | - | - | - |
Deep-Palm: 0.48
|
|
| 278 | - | - | - |
Deep-Palm: 0.09
|
|
| 304 | - | - | - |
Deep-Palm: 0.64
|
|
| 310 | - | - | - |
Deep-Palm: 0.75
|
|
| 311 | - | - | - |
Deep-Palm: 0.81
|
|
| 328 | - | - | - |
Deep-Palm: 0.29
|
|
| 329 | - |
HeLa
(29575903)
| - | - | |
| 330 | - |
HeLa
(29575903)
| - | - | |
| 397 | - | - | - |
Deep-Palm: 0.86
|
|
| 465 | - | - | - |
Deep-Palm: 0.93
|
|
| 519 | - | - | - |
Deep-Palm: 0.93
|
|
| 610 | - | - | - |
Deep-Palm: 0.69
|
|
| 611 | - | - | - |
Deep-Palm: 0.66
|
|
| 658 | - | - | - |
Deep-Palm: 0.94
|
|
| 661 | - | - | - |
Deep-Palm: 0.36
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.375
3
LNCaP
Specificity: 0.375
3/3 (100.0%)
3
cerebral cortex
Specificity: 0.375
3/3 (100.0%)
1
HeLa cell
Specificity: 0.125
1/1 (100.0%)
1
Jurkat T cell
Specificity: 0.125
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 125 | C → C | 0.002288 | SNP | Silent | STAD |
| 125 | C → C | 0.001887 | SNP | Silent | UCEC |
| 191 | S → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 201 | C → C | 0.002020 | SNP | Silent | PRAD |
| 278 | C → C | 0.001887 | SNP | Silent | UCEC |
| 616 | Y → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 658 | C → C | 0.002506 | SNP | Silent | COAD |