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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8NFJ5 GPRC5A; GPCR5A; RAI3; RAIG1 Retinoic acid-induced protein 3 (G-protein … Homo sapiens (Human) 357 aa

Protein Details: Q8NFJ5 (GPRC5A)

Protein Information
Accession Q8NFJ5
Protein Names Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Phorbol ester induced gene 1) (PEIG-1) (Retinoic acid-induced gene 1 protein) (RAIG-1)
Gene Symbol GPRC5A; GPCR5A; RAI3; RAIG1
Organism Homo sapiens (Human)
Length 357 aa
Isoforms No isoforms
Related PMIDs 19801377 22496122 24357059 29575903 37611173
Database Sources dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
2
DU145 cells
Specificity: 0.400
2/2 (100.0%)
2
Endothelial cells
Specificity: 0.400
2/2 (100.0%)
1
HeLa cells
Specificity: 0.200
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MATTVPDGCR11NGLKSKYYRL21CDKAEAWGIV31LETVATAGVV41TSVAFMLTLP
51-10051ILVCKVQDSN61RRKMLPTQFL71FLLGVLGIFG81LTFAFIIGLD91GSTGPTRFFL
101-150101FGILFSICFS111CLLAHAVSLT121KLVRGRKPLS131LLVILGLAVG141FSLVQDVIAI
151-200151EYIVLTMNRT161NVNVFSELSA171PRRNEDFVLL181LTYVLFLMAL191TFLMSSFTFC
201-250201GSFTGWKRHG211AHIYLTMLLS221IAIWVAWITL231LMLPDFDRRW241DDTILSSALA
251-300251ANGWVFLLAY261VSPEFWLLTK271QRNPMDYPVE281DAFCKPQLVK291KSYGVENRAY
301-350301SQEEITQGFE311ETGDTLYAPY321STHFQLQNQP331PQKEFSIPRA341HAWPSPYKDY
351-357351EVKKEGS
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
9 Experimental DBPTM SWISSPALM Prediction (High) - 19801377
21 Prediction (Low) - -
54 Prediction (High) - -
108 Prediction (Low) - -
111 Prediction (Low) - -
200 Prediction (Medium) - -
284 Experimental DBPTM SWISSPALM - 37611173, 19801377
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
110 S → Cfs*42 0.001764 INS Frame Shift Ins LUAD
172 R → C 0.003460 SNP Missense Mutation CESC
? ? → ? 0.002545 SNP Missense Mutation GBM
? ? → ? 0.001887 SNP Silent UCEC