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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8QZS1 Hibch 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4) … Mus musculus (Mouse) 385 aa

Protein Details: Q8QZS1 (Hibch)

Protein Information
AccessionQ8QZS1
Protein Names3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4) (3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H)
Gene SymbolHibch
OrganismMus musculus (Mouse)
Length385 aa
IsoformsNo isoforms
Related PMIDs 28526873 29660268 34884899 35358180 35477839 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MGQPYAWRLL11SRVSSFRRAS21VILQHLRMSM31HTEAAEVLLE41RRGCGGVITL
51-10051NRPKFLNALS61LNMIRQIYPQ71LKTWEQDPDT81FLIIIKGAGG91KAFCAGGDIK
101-150101ALSEAKKARQ111NLTQDLFREE121YILNNAIASC131QKPYVALIDG141ITMGGGVGLS
151-200151VHGQFRVATE161RSLFAMPETG171IGLFPDVGGG181YFLPRLQGKL191GYFLALTGYR
201-250201LKGRDVHRAG211IATHFVDSEK221LRVLEEELLA231LKSPSAEDVA241GVLESYHAKS
251-300251KMDQDKSIIF261EEHMDKINSC271FSANTVEQII281ENLRQDGSPF291AIEQMKVINK
301-350301MSPTSLKITL311RQLMEGSSKT321LQEVLIMEYR331ITQACMEGHD341FHEGVRAVLI
351-385351DKDQTPKWKP361ANLKDVTDED371LNSYFKSLGS381SDLKF
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
44 SWISSPALM DBPTM CYSMODDB ClpP/crotonase-like domain superfamily
liver (26165157)
-
GPS-Palm: 0.96
Deep-Palm: 0.98
94 - - -
GPS-Palm: 0.93
Deep-Palm: 0.97
130 - - -
Deep-Palm: 0.78
270 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
-
Deep-Palm: 0.11
335 SWISSPALM DBPTM CYSMODDB Enoyl-CoA hydratase/isomerase
Forebrain (28680068)
-
Deep-Palm: 0.94
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.556
5
Liver
Specificity: 0.556
5/5 (100.0%)
2
Brain
Specificity: 0.222
2/2 (100.0%)
2
Testis
Specificity: 0.222
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine