Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8QZT1 Acat1 Acetyl-CoA acetyltransferase, mitochondrial (EC 2.3.1.9) … Mus musculus (Mouse) 424 aa

Protein Details: Q8QZT1 (Acat1)

Protein Information
AccessionQ8QZT1
Protein NamesAcetyl-CoA acetyltransferase, mitochondrial (EC 2.3.1.9) (Acetoacetyl-CoA thiolase)
Gene SymbolAcat1
OrganismMus musculus (Mouse)
Length424 aa
IsoformsNo isoforms
Related PMIDs 28526873 29733200 31311849 34200797 34884899 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAALVALHGV11VRRPLLRGLL21QEVRCLERSY31ASKPTLNEVV41IVSAIRTPIG
51-10051SFLGSLASQP61ATKLGTAAIQ71GAIEKAGIPK81EEVKEVYMGN91VIQGGEGQAP
101-150101TRQATLGAGL111PISTPCTTVN121KVCASGMKAI131MMASQSLMCG141HQDVMVAGGM
151-200151ESMSNVPYVM161SRGATPYGGV171KLEDLIVKDG181LTDVYNKIHM191GNCAENTAKK
201-250201MNISRQEQDT211YALSSYTRSK221EAWDAGKFAS231EITPITISVK241GKPDVVVKED
251-300251EEYKRVDFSK261VPKLKTVFQK271ENGTITAANA281STLNDGAAAL291VLMTAEAAQR
301-350301LNVKPLARIA311AFADAAVDPI321DFPLAPAYAV331PKVLKYAGLK341KEDIAMWEVN
351-400351EAFSVVVLAN361IKMLEIDPQK371VNIHGGAVSL381GHPIGMSGAR391IVVHMAHALK
401-424401PGEFGLASIC411NGGGGASALL421IEKL
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
25 - - -
Deep-Palm: 0.98
116 SWISSPALM DBPTM CYSMODDB Thiolase N-terminal domain
Brain (31311849)
MLE (39008777)
Liver (28526873)
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.97
123 SWISSPALM DBPTM CYSMODDB Thiolase N-terminal domain
Forebrain (28680068)
-
Deep-Palm: 0.93
139 - - -
Deep-Palm: 0.89
193 SWISSPALM DBPTM CYSMODDB Thiolase N-terminal domain
Liver (28526873)
Brain (35358180)
Deep-Palm: 0.36
410 - -
Brain (35358180)
Deep-Palm: 0.98
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.545
6
Liver
Specificity: 0.136
6/6 (100.0%)
5
Brain
Specificity: 0.114
5/5 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
33
Brain tissue (Mass)
Specificity: 0.750
33/56 (58.9%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine