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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8R0I4 Tm2d2 TM2 domain-containing protein 2 Mus musculus (Mouse) 213 aa

Protein Details: Q8R0I4 (Tm2d2)

Protein Information
AccessionQ8R0I4
Protein NamesTM2 domain-containing protein 2
Gene SymbolTm2d2
OrganismMus musculus (Mouse)
Length213 aa
IsoformsNo isoforms
Related PMIDs 29217618 31772009 34200797 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MVLGGCPVSY11LLLCGQAALL21LGNLLLLHCV31SRSHSFNATA41ELDLTPSGAA
51-10051HLEGPAASSW61EYSDPNSPVI71LCSYLPDEFV81DCDAPVDHVG91NATASQELGY
101-150101GCLKFGGQAY111SDVQHTAVQC121RALEGIECAS131PRTFLRENKP141CIKYTGHYFI
151-200151TTLLYSFFLG161CFGVDRFCLG171HTGTAVGKLL181TLGGLGIWWF191VDLILLITGG
201-213201LMPSDGSNWC211TVY
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
6 - - -
GPS-Palm: 0.82
Deep-Palm: 0.09
14 - - -
Deep-Palm: 0.98
29 - - -
GPS-Palm: 0.74
Deep-Palm: 0.98
72 - - -
Deep-Palm: 0.20
82 - - -
Deep-Palm: 0.21
102 - - -
GPS-Palm: 0.72
Deep-Palm: 0.79
120 -
brain (39008777)
Brain (35358180)
Deep-Palm: 0.67
128 -
brain (39008777)
MLE (39008777)
Brain (35358180)
GPS-Palm: 0.84
Deep-Palm: 0.77
141 - - -
GPS-Palm: 0.74
Deep-Palm: 0.43
161 - - -
GPS-Palm: 0.85
Deep-Palm: 0.83
168 SWISSPALM DBPTM CYSMODDB TM2 domain
Forebrain (28680068)
-
GPS-Palm: 0.83
Deep-Palm: 0.98
210 - - -
GPS-Palm: 0.96
Deep-Palm: 0.02
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.333
2
Testis
Specificity: 0.143
2/2 (100.0%)
1
Raw 264.7
Specificity: 0.071
1/1 (100.0%)
1
NSC
Specificity: 0.071
1/1 (100.0%)
1
Brain
Specificity: 0.071
1/1 (100.0%)
1
Liver
Specificity: 0.071
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
8
Brain tissue (Mass)
Specificity: 0.571
8/56 (14.3%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine