Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8R0Y6 | Aldh1l1 | Cytosolic 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) (FDH) … | Mus musculus (Mouse) | 902 aa |
Protein Details: Q8R0Y6 (Aldh1l1)
Protein Information
| Accession | Q8R0Y6 |
|---|---|
| Protein Names | Cytosolic 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) (FDH) (EC 1.5.1.6) (Aldehyde dehydrogenase family 1 member L1) |
| Gene Symbol | Aldh1l1 |
| Organism | Mus musculus (Mouse) |
| Length | 902 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29733200 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MKIAVIGQSL11FGQEVYCQLR21KEGHEVVGVF31TIPDKDGKAD41PLGLEAEKDG
51-10051VPVFKFPRWR61ARGQALPEVV71AKYQALGAEL81NVLPFCSQFI91PMEVINAPRH
101-150101GSIIYHPSLL111PRHRGASAIN121WTLIHGDKKG131GFTIFWADDG141LDTGDLLLQK
151-200151ECDVLPDDTV161STLYNRFLFP171EGIKGMVQAV181RLIAEGTAPR191RPQPEEGATY
201-250201EGIQKKETAM211INWDQPAEAI221HNWIRGNDKV231PGAWTEACGQ241KLTFFNSTLN
251-300251TSGLVAQGEA261LPIPGAHRPG271LVTKAGLILF281GNDDRMLLVK291NIQLEDGKMM
301-350301PASQFFKGSA311SSALELTEEE321LATAEAVRSS331WMRILPNVPE341VEDSTDFFKS
351-400351GAASVDVVRL361VEEVKELCDG371LELENEDVYM381ATTFGDFIQL391LVRKLRGEDG
401-450401ESECVINYVE411KAVKKLTLQM421PYQLFIGGEF431VDAEGAKTYS441TINPTDGSVI
451-500451CQVSLAQVSD461VDKAVAAAKE471AFENGLWGKI481NARDRGRLLY491RLADLMEQHQ
501-550501EELATIEALD511AGAVYTLALK521THVGMSIQTF531RYFAGWCDKI541QGATIPINQA
551-600551RPNRNLTLTK561KEPVGVCGIV571IPWNYPLMML581SWKTAACLAA591GNTVVIKPAQ
601-650601VTPLTALKFA611ELTLKAGIPK621GVVNILPGSG631SLVGQRLSDH641PDVRKIGFTG
651-700651STEVGKHIMK661SCALSNVKKV671SLELGGKSPL681IIFADCDLNK691AVQMGMSSVF
701-750701FNKGENCIAA711GRLFVEDSIH721DQFVQKVVEE731VGKMKIGNPL741DRDTNHGPQN
751-800751HEAHLRKLVE761YCQRGVKEGA771TLVCGGNQVP781RPGFFFQPTV791FTDVEDHMYI
801-850801AKEESFGPIM811IISRFADGDV821DAVLSRANAT831EFGLASGVFT841RDINKALYVS
851-900851DKLQAGTVFV861NTYNKTDVAA871PFGGFKQSGF881GKDLGEAALN891EYLRIKTVTF
901-902901EY
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 17 | SWISSPALM DBPTM CYSMODDB | - |
liver
(26165157)
|
Brain
(35358180)
|
Deep-Palm: 0.93
|
| 86 | SWISSPALM DBPTM CYSMODDB | Formyl transferase |
Liver
(28526873)
| - |
Deep-Palm: 0.95
|
| 152 | SWISSPALM DBPTM CYSMODDB | Formyl transferase |
Liver
(28526873)
|
Brain
(35358180)
|
Deep-Palm: 0.92
|
| 238 | SWISSPALM DBPTM CYSMODDB | Formyl transferase C-terminal domain |
Liver
(28526873)
|
Brain
(35358180)
|
Deep-Palm: 0.68
|
| 368 | - | - | - |
Deep-Palm: 0.93
|
|
| 404 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
|
Brain
(35358180)
|
Deep-Palm: 0.98
|
| 451 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.97
|
|
| 537 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
| - |
Deep-Palm: 0.48
|
| 567 | - | - | - |
Deep-Palm: 0.53
|
|
| 587 | SWISSPALM DBPTM CYSMODDB | Aldehyde dehydrogenase family |
liver
(26165157)
Liver
(28526873)
| - |
Deep-Palm: 0.79
|
| 662 | SWISSPALM DBPTM CYSMODDB | Aldehyde dehydrogenase family |
liver
(26165157)
| - |
GPS-Palm: 0.90
Deep-Palm: 0.97
|
| 686 | SWISSPALM DBPTM CYSMODDB | Aldehyde dehydrogenase family |
Liver
(28526873)
|
Brain
(35358180)
|
Deep-Palm: 0.98
|
| 707 | - | - | - |
Deep-Palm: 0.56
|
|
| 762 | SWISSPALM DBPTM CYSMODDB | Aldehyde dehydrogenase family |
liver
(26165157)
|
Liver
(37925639)
Brain
(35358180)
|
Deep-Palm: 0.97
|
| 774 | SWISSPALM DBPTM CYSMODDB | Aldehyde dehydrogenase family |
liver
(26165157)
|
Brain
(35358180)
|
GPS-Palm: 0.90
Deep-Palm: 0.95
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
6
Liver
Specificity: 0.150
6/6 (100.0%)
2
Brain
Specificity: 0.050
2/2 (100.0%)
2
Testis
Specificity: 0.050
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
24
Brain tissue (Mass)
Specificity: 0.600
24/56 (42.9%)
6
Liver tissue (Mass)
Specificity: 0.150
6/8 (75.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.