Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8TCJ2 | STT3B; SIMP | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (Oligosaccharyl … | Homo sapiens (Human) | 826 aa |
Protein Details: Q8TCJ2 (STT3B)
Protein Information
| Accession | Q8TCJ2 |
|---|---|
| Protein Names | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (Oligosaccharyl transferase subunit STT3B) (STT3-B) (EC 2.4.99.18) (Source of immunodominant MHC-associated peptides homolog) |
| Gene Symbol | STT3B; SIMP |
| Organism | Homo sapiens (Human) |
| Length | 826 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 21076176 29733200 31251020 31382980 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.574
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
35
LNCaP cells
Specificity: 0.574
35/46 (76.1%)
10
HAP1 cells
Specificity: 0.164
10/10 (100.0%)
6
Jurkat T cells
Specificity: 0.098
6/25 (24.0%)
6
293T cells
Specificity: 0.098
6/10 (60.0%)
3
PC3 cells
Specificity: 0.049
3/4 (75.0%)
1
U937 cells
Specificity: 0.016
1/1 (100.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAEPSAPESK11HKSSLNSSPW21SGLMALGNSR31HGHHGPGAQC41AHKAAGGAAP
51-10051PKPAPAGLSG61GLSQPAGWQS71LLSFTILFLA81WLAGFSSRLF91AVIRFESIIH
101-150101EFDPWFNYRS111THHLASHGFY121EFLNWFDERA131WYPLGRIVGG141TVYPGLMITA
151-200151GLIHWILNTL161NITVHIRDVC171VFLAPTFSGL181TSISTFLLTR191ELWNQGAGLL
201-250201AACFIAIVPG211YISRSVAGSF221DNEGIAIFAL231QFTYYLWVKS241VKTGSVFWTM
251-300251CCCLSYFYMV261SAWGGYVFII271NLIPLHVFVL281LLMQRYSKRV291YIAYSTFYIV
301-350301GLILSMQIPF311VGFQPIRTSE321HMAAAGVFAL331LQAYAFLQYL341RDRLTKQEFQ
351-400351TLFFLGVSLA361AGAVFLSVIY371LTYTGYIAPW381SGRFYSLWDT391GYAKIHIPII
401-450401ASVSEHQPTT411WVSFFFDLHI421LVCTFPAGLW431FCIKNINDER441VFVALYAISA
451-500451VYFAGVMVRL461MLTLTPVVCM471LSAIAFSNVF481EHYLGDDMKR491ENPPVEDSSD
501-550501EDDKRNQGNL511YDKAGKVRKH521ATEQEKTEEG531LGPNIKSIVT541MLMLMLLMMF
551-600551AVHCTWVTSN561AYSSPSVVLA571SYNHDGTRNI581LDDFREAYFW591LRQNTDEHAR
601-650601VMSWWDYGYQ611IAGMANRTTL621VDNNTWNNSH631IALVGKAMSS641NETAAYKIMR
651-700651TLDVDYVLVI661FGGVIGYSGD671DINKFLWMVR681IAEGEHPKDI691RESDYFTPQG
701-750701EFRVDKAGSP711TLLNCLMYKM721SYYRFGEMQL731DFRTPPGFDR741TRNAEIGNKD
751-800751IKFKHLEEAF761TSEHWLVRIY771KVKAPDNRET781LDHKPRVTNI791FPKQKYLSKK
801-826801TTKRKRGYIK811NKLVFKKGKK821ISKKTV
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 170 | Prediction (Low) | - | - |
| 251 | Prediction (Low) | - | - |
| 252 | Prediction (Low) | - | - |
| 432 | Prediction (Medium) | - | - |
| 469 | Prediction (Low) | - | - |
| 715 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 251 | C → Y | 0.001969 | SNP | Missense Mutation | LGG |
| 298 | Y → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 452 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 626 | W → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 627 | N → delinsISCIY | 0.001887 | INS | In Frame Ins | UCEC |
| 742 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 742 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 806 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |