Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8TEA1 NSUN6 tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 (EC 2.1.1.-) … Homo sapiens (Human) 469 aa

Protein Details: Q8TEA1 (NSUN6)

Protein Information
AccessionQ8TEA1
Protein NamestRNA (cytosine(72)-C(5))-methyltransferase NSUN6 (EC 2.1.1.-) (NOL1/NOP2/Sun and PUA domain-containing protein 1) (NOL1/NOP2/Sun domain family member 6)
Gene SymbolNSUN6
OrganismHomo sapiens (Human)
Length469 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSIFPKISLR11PEVENYLKEG21FMNKEIVTAL31GKQEAERKFE41TLLKHLSHPP
51-10051SFTTVRVNTH61LASVQHVKNL71LLDELQKQFN81GLSVPILQHP91DLQDVLLIPV
101-150101IGPRKNIKKQ111QCEAIVGAQC121GNAVLRGAHV131YAPGIVSASQ141FMKAGDVISV
151-200151YSDIKGKCKK161GAKEFDGTKV171FLGNGISELS181RKEIFSGLPE191LKGMGIRMTE
201-250201PVYLSPSFDS211VLPRYLFLQN221LPSALVSHVL231NPQPGEKILD241LCAAPGGKTT
251-300251HIAALMHDQG261EVIALDKIFN271KVEKIKQNAL281LLGLNSIRAF291CFDGTKAVKL
301-350301DMVEDTEGEP311PFLPESFDRI321LLDAPCSGMG331QRPNMACTWS341VKEVASYQPL
351-400351QRKLFTAAVQ361LLKPEGVLVY371STCTITLAEN381EEQVAWALTK391FPCLQLQPQE
401-450401PQIGGEGMRG411AGLSCEQLKQ421LQRFDPSAVP431LPDTDMDSLR441EARREDMLRL
451-469451ANKDSIGFFI461AKFVKCKST
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
112 - - -
Deep-Palm: 0.82
120 - - -
Deep-Palm: 0.82
158 - - -
GPS-Palm: 0.72
Deep-Palm: 0.97
242 - - -
GPS-Palm: 0.86
Deep-Palm: 0.96
291 - - -
GPS-Palm: 0.94
Deep-Palm: 0.97
326 - - -
GPS-Palm: 0.87
Deep-Palm: 0.95
337 - - -
Deep-Palm: 0.63
373 - - -
Deep-Palm: 0.97
393 - - -
GPS-Palm: 0.84
Deep-Palm: 0.89
415 SWISSPALM DBPTM CYSMODDB - - -
GPS-Palm: 0.93
Deep-Palm: 0.98
466 - - -
GPS-Palm: 0.96
Deep-Palm: 0.03
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
242 C → Y 0.001969 SNP Missense Mutation HNSC
449 R → C 0.001887 SNP Missense Mutation UCEC
459 F → C 0.001887 SNP Missense Mutation UCEC
463 F → C 0.002427 SNP Missense Mutation BLCA
463 F → C 0.001887 SNP Missense Mutation UCEC
? ? → ? 0.001764 SNP Missense Mutation LUAD