Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8TEQ6 | GEMIN5 | Gem-associated protein 5 (Gemin5) | Homo sapiens (Human) | 1508 aa |
Protein Details: Q8TEQ6 (GEMIN5)
Protein Information
| Accession | Q8TEQ6 |
|---|---|
| Protein Names | Gem-associated protein 5 (Gemin5) |
| Gene Symbol | GEMIN5 |
| Organism | Homo sapiens (Human) |
| Length | 1508 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 29733200 31251020 31382980 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.286
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
4
HAP1 cells
Specificity: 0.286
4/10 (40.0%)
4
293T cells
Specificity: 0.286
4/10 (40.0%)
2
LNCaP cells
Specificity: 0.143
2/46 (4.3%)
2
PC3 cells
Specificity: 0.143
2/4 (50.0%)
1
U937 cells
Specificity: 0.071
1/1 (100.0%)
1
HeLa cells
Specificity: 0.071
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGQEPRTLPP11SPNWYCARCS21DAVPGGLFGF31AARTSVFLVR41VGPGAGESPG
51-10051TPPFRVIGEL61VGHTERVSGF71TFSHHPGQYN81LCATSSDDGT91VKIWDVETKT
101-150101VVTEHALHQH111TISTLHWSPR121VKDLIVSGDE131KGVVFCYWFN141RNDSQHLFIE
151-200151PRTIFCLTCS161PHHEDLVAIG171YKDGIVVIID181ISKKGEVIHR191LRGHDDEIHS
201-250201IAWCPLPGED211CLSINQEETS221EEAEITNGNA231VAQAPVTKGC241YLATGSKDQT
251-300251IRIWSCSRGR261GVMILKLPFL271KRRGGGIDPT281VKERLWLTLH291WPSNQPTQLV
301-350301SSCFGGELLQ311WDLTQSWRRK321YTLFSASSEG331QNHSRIVFNL341CPLQTEDDKQ
351-400351LLLSTSMDRD361VKCWDIATLE371CSWTLPSLGG381FAYSLAFSSV391DIGSLAIGVG
401-450401DGMIRVWNTL411SIKNNYDVKN421FWQGVKSKVT431ALCWHPTKEG441CLAFGTDDGK
451-500451VGLYDTYSNK461PPQISSTYHK471KTVYTLAWGP481PVPPMSLGGE491GDRPSLALYS
501-550501CGGEGIVLQH511NPWKLSGEAF521DINKLIRDTN531SIKYKLPVHT541EISWKADGKI
551-600551MALGNEDGSI561EIFQIPNLKL571ICTIQQHHKL581VNTISWHHEH591GSQPELSYLM
601-650601ASGSNNAVIY611VHNLKTVIES621SPESPVTITE631PYRTLSGHTA641KITSVAWSPH
651-700651HDGRLVSASY661DGTAQVWDAL671REEPLCNFRG681HRGRLLCVAW691SPLDPDCIYS
701-750701GADDFCVHKW711LTSMQDHSRP721PQGKKSIELE731KKRLSQPKAK741PKKKKKPTLR
751-800751TPVKLESIDG761NEEESMKENS771GPVENGVSDQ781EGEEQAREPE791LPCGLAPAVS
801-850801REPVICTPVS811SGFEKSKVTI821NNKVILLKKE831PPKEKPETLI841KKRKARSLLP
851-900851LSTSLDHRSK861EELHQDCLVL871ATAKHSRELN881EDVSADVEER891FHLGLFTDRA
901-950901TLYRMIDIEG911KGHLENGHPE921LFHQLMLWKG931DLKGVLQTAA941ERGELTDNLV
951-1000951AMAPAAGYHV961WLWAVEAFAK971QLCFQDQYVK981AASHLLSIHK991VYEAVELLKS
1001-10501001NHFYREAIAI1011AKARLRPEDP1021VLKDLYLSWG1031TVLERDGHYA1041VAAKCYLGAT
1051-11001051CAYDAAKVLA1061KKGDAASLRT1071AAELAAIVGE1081DELSASLALR1091CAQELLLANN
1101-11501101WVGAQEALQL1111HESLQGQRLV1121FCLLELLSRH1131LEEKQLSEGK1141SSSSYHTWNT
1151-12001151GTEGPFVERV1161TAVWKSIFSL1171DTPEQYQEAF1181QKLQNIKYPS1191ATNNTPAKQL
1201-12501201LLHICHDLTL1211AVLSQQMASW1221DEAVQALLRA1231VVRSYDSGSF1241TIMQEVYSAF
1251-13001251LPDGCDHLRD1261KLGDHQSPAT1271PAFKSLEAFF1281LYGRLYEFWW1291SLSRPCPNSS
1301-13501301VWVRAGHRTL1311SVEPSQQLDT1321ASTEETDPET1331SQPEPNRPSE1341LDLRLTEEGE
1351-14001351RMLSTFKELF1361SEKHASLQNS1371QRTVAEVQET1381LAEMIRQHQK1391SQLCKSTANG
1401-14501401PDKNEPEVEA1411EQPLCSSQSQ1421CKEEKNEPLS1431LPELTKRLTE1441ANQRMAKFPE
1451-15001451SIKAWPFPDV1461LECCLVLLLI1471RSHFPGCLAQ1481EMQQQAQELL1491QKYGNTKTYR
1501-15081501RHCQTFCM
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 240 | Prediction (Medium) | - | - |
| 256 | Prediction (Low) | - | - |
| 341 | Prediction (Low) | - | - |
| 441 | Prediction (Low) | - | - |
| 572 | Prediction (High) | - | - |
| 676 | Prediction (Medium) | - | - |
| 687 | Prediction (Medium) | - | - |
| 793 | Prediction (Low) | - | - |
| 806 | Prediction (Low) | - | - |
| 973 | Prediction (Medium) | - | - |
| 1051 | Prediction (Medium) | - | - |
| 1122 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) | - | 29575903 |
| 1255 | Prediction (Low) | - | - |
| 1394 | Prediction (Low) | - | - |
| 1463 | Prediction (Medium) | - | - |
| 1464 | Prediction (Low) | - | - |
| 1477 | Prediction (Medium) | - | - |
| 1503 | Prediction (High) | - | - |
| 1507 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 82 | C → C | 0.001887 | SNP | Silent | UCEC |
| 200 | S → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 284 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 706 | C → Vfs*44 | 0.002288 | DEL | Frame Shift Del | STAD |
| 806 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 973 | C → Y | 0.006944 | SNP | Missense Mutation | TGCT |
| 983 | S → C | 0.003460 | SNP | Missense Mutation | CESC |
| 1145 | Y → C | 0.002506 | SNP | Missense Mutation | COAD |
| 1205 | C → C | 0.002506 | SNP | Silent | COAD |
| 1284 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 1421 | C → F | 0.001764 | SNP | Missense Mutation | LUAD |