Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8TF72 SHROOM3 Protein Shroom3 (Shroom-related protein) (hShrmL) Homo sapiens (Human) 1996 aa

Protein Details: Q8TF72 (SHROOM3)

Protein Information
AccessionQ8TF72
Protein NamesProtein Shroom3 (Shroom-related protein) (hShrmL)
Gene SymbolSHROOM3
OrganismHomo sapiens (Human)
Length1996 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MMRTTEDFHK11PSATLNSNTA21TKGRYIYLEA31FLEGGAPWGF41TLKGGLEHGE
51-10051PLIISKVEEG61GKADTLSSKL71QAGDEVVHIN81EVTLSSSRKE91AVSLVKGSYK
101-150101TLRLVVRRDV111CTDPGHADTG121ASNFVSPEHL131TSGPQHRKAA141WSGGVKLRLK
151-200151HRRSEPAGRP161HSWHTTKSGE171KQPDASMMQI181SQGMIGPPWH191QSYHSSSSTS
201-250201DLSNYDHAYL211RRSPDQCSSQ221GSMESLEPSG231AYPPCHLSPA241KSTGSIDQLS
251-300251HFHNKRDSAY261SSFSTSSSIL271EYPHPGISGR281ERSGSMDNTS291ARGGLLEGMR
301-350301QADIRYVKTV311YDTRRGVSAE321YEVNSSALLL331QGREARASAN341GQGYDKWSNI
351-400351PRGKGVPPPS361WSQQCPSSLE371TATDNLPPKV381GAPLPPARSD391SYAAFRHRER
401-450401PSSWSSLDQK411RLCRPQANSL421GSLKSPFIEE431QLHTVLEKSP441ENSPPVKPKH
451-500451NYTQKAQPGQ461PLLPTSIYPV471PSLEPHFAQV481PQPSVSSNGM491LYPALAKESG
501-550501YIAPQGACNK511MATIDENGNQ521NGSGRPGFAF531CQPLEHDLLS541PVEKKPEATA
551-600551KYVPSKVHFC561SVPENEEDAS571LKRHLTPPQG581NSPHSNERKS591THSNKPSSHP
601-650601HSLKCPQAQA611WQAGEDKRSS621RLSEPWEGDF631QEDHNANLWR641RLEREGLGQS
651-700651LSGNFGKTKS661AFSSLQNIPE671SLRRHSSLEL681GRGTQEGYPG691GRPTCAVNTK
701-750701AEDPGRKAAP711DLGSHLDRQV721SYPRPEGRTG731ASASFNSTDP741SPEEPPAPSH
751-800751PHTSSLGRRG761PGPGSASALQ771GFQYGKPHCS781VLEKVSKFEQ791REQGSQRPSV
801-850801GGSGFGHNYR811PHRTVSTSST821SGNDFEETKA831HIRFSESAEP841LGNGEQHFKN
851-900851GELKLEEASR861QPCGQQLSGG871ASDSGRGPQR881PDARLLRSQS891TFQLSSEPER
901-950901EPEWRDRPGS911PESPLLDAPF921SRAYRNSIKD931AQSRVLGATS941FRRRDLELGA
951-1000951PVASRSWRPR961PSSAHVGLRS971PEASASASPH981TPRERHSVTP991AEGDLARPVP
1001-10501001PAARRGARRR1011LTPEQKKRSY1021SEPEKMNEVG1031IVEEAEPAPL1041GPQRNGMRFP
1051-11001051ESSVADRRRL1061FERDGKACST1071LSLSGPELKQ1081FQQSALADYI1091QRKTGKRPTS
1101-11501101AAGCSLQEPG1111PLRERAQSAY1121LQPGPAALEG1131SGLASASSLS1141SLREPSLQPR
1151-12001151REATLLPATV1161AETQQAPRDR1171SSSFAGGRRL1181GERRRGDLLS1191GANGGTRGTQ
1201-12501201RGDETPREPS1211SWGARAGKSM1221SAEDLLERSD1231VLAGPVHVRS1241RSSPATADKR
1251-13001251QDVLLGQDSG1261FGLVKDPCYL1271AGPGSRSLSC1281SERGQEEMLP1291LFHHLTPRWG
1301-13501301GSGCKAIGDS1311SVPSECPGTL1321DHQRQASRTP1331CPRPPLAGTQ1341GLVTDTRAAP
1351-14001351LTPIGTPLPS1361AIPSGYCSQD1371GQTGRQPLPP1381YTPAMMHRSN1391GHTLTQPPGP
1401-14501401RGCEGDGPEH1411GVEEGTRKRV1421SLPQWPPPSR1431AKWAHAARED1441SLPEESSAPD
1451-15001451FANLKHYQKQ1461QSLPSLCSTS1471DPDTPLGAPS1481TPGRISLRIS1491ESVLRDSPPP
1501-15501501HEDYEDEVFV1511RDPHPKATSS1521PTFEPLPPPP1531PPPPSQETPV1541YSMDDFPPPP
1551-16001551PHTVCEAQLD1561SEDPEGPRPS1571FNKLSKVTIA1581RERHMPGAAH1591VVGSQTLASR
1601-16501601LQTSIKGSEA1611ESTPPSFMSV1621HAQLAGSLGG1631QPAPIQTQSL1641SHDPVSGTQG
1651-17001651LEKKVSPDPQ1661KSSEDIRTEA1671LAKEIVHQDK1681SLADILDPDS1691RLKTTMDLME
1701-17501701GLFPRDVNLL1711KENSVKRKAI1721QRTVSSSGCE1731GKRNEDKEAV1741SMLVNCPAYY
1751-18001751SVSAPKAELL1761NKIKEMPAEV1771NEEEEQADVN1781EKKAELIGSL1791THKLETLQEA
1801-18501801KGSLLTDIKL1811NNALGEEVEA1821LISELCKPNE1831FDKYRMFIGD1841LDKVVNLLLS
1851-19001851LSGRLARVEN1861VLSGLGEDAS1871NEERSSLYEK1881RKILAGQHED1891ARELKENLDR
1901-19501901RERVVLGILA1911NYLSEEQLQD1921YQHFVKMKST1931LLIEQRKLDD1941KIKLGQEQVK
1951-19961951CLLESLPSDF1961IPKAGALALP1971PNLTSEPIPA1981GGCTFSGIFP1991TLTSPL
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
111 - - -
GPS-Palm: 0.76
Deep-Palm: 0.94
217 - - -
Deep-Palm: 0.41
235 - - -
Deep-Palm: 0.79
365 - - -
Deep-Palm: 0.76
413 SWISSPALM DBPTM CYSMODDB - - -
GPS-Palm: 0.81
Deep-Palm: 0.96
508 - - -
GPS-Palm: 0.74
Deep-Palm: 0.76
531 - - -
Deep-Palm: 0.76
560 - - -
Deep-Palm: 0.88
605 - - -
Deep-Palm: 0.43
695 - - -
Deep-Palm: 0.88
779 - - -
GPS-Palm: 0.86
Deep-Palm: 0.87
863 - - -
Deep-Palm: 0.95
1068 - - -
GPS-Palm: 0.89
Deep-Palm: 0.98
1104 - - -
GPS-Palm: 0.88
Deep-Palm: 0.97
1268 - - -
GPS-Palm: 0.91
Deep-Palm: 0.96
1280 - - -
GPS-Palm: 0.65
Deep-Palm: 0.91
1304 - - -
GPS-Palm: 0.72
Deep-Palm: 0.72
1316 - - -
Deep-Palm: 0.75
1331 - - -
GPS-Palm: 0.66
Deep-Palm: 0.86
1367 - - -
Deep-Palm: 0.76
1403 - - -
Deep-Palm: 0.58
1467 - - -
Deep-Palm: 0.88
1555 - - -
Deep-Palm: 0.33
1729 - - -
GPS-Palm: 0.80
Deep-Palm: 0.94
1746 - - -
Deep-Palm: 0.72
1826 - - -
GPS-Palm: 0.74
Deep-Palm: 0.96
1951 - - -
GPS-Palm: 0.79
Deep-Palm: 0.98
1983 - - -
Deep-Palm: 0.93
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
17 S → C 0.002427 SNP Missense Mutation BLCA
44 G → C 0.001887 SNP Missense Mutation UCEC
107 R → C 0.001764 SNP Missense Mutation LUAD
107 R → C 0.002294 SNP Missense Mutation OV
278 S → C 0.001969 SNP Missense Mutation HNSC
305 R → C 0.001969 SNP Missense Mutation LGG
398 R → C 0.002506 SNP Missense Mutation COAD
560 C → F 0.002427 SNP Missense Mutation BLCA
734 S → C 0.002976 SNP Missense Mutation KIRC
1018 R → C 0.002506 SNP Missense Mutation COAD
1048 R → C 0.002288 SNP Missense Mutation STAD
1250 R → C 0.002141 SNP Missense Mutation SKCM
1568 R → C 0.001014 SNP Missense Mutation BRCA
1701 G → C 0.002033 SNP Missense Mutation LUSC
1750 Y → C 0.002427 SNP Missense Mutation BLCA
1900 R → C 0.002506 SNP Missense Mutation COAD