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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8VBT0 Tmx1 Thioredoxin-related transmembrane protein 1 (Protein … Mus musculus (Mouse) 278 aa

Protein Details: Q8VBT0 (Tmx1)

Protein Information
AccessionQ8VBT0
Protein NamesThioredoxin-related transmembrane protein 1 (Protein disulfide-isomerase TMX1) (EC 5.3.4.1) (Thioredoxin domain-containing protein 1)
Gene SymbolTmx1
OrganismMus musculus (Mouse)
Length278 aa
IsoformsNo isoforms
Related PMIDs 28526873 29217618 29575903 29733200 31772009 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAHLGRLMVP11LAALVLLLWA21VPGAHGRRNN31VRVLTDENWT41SLLEGEWMIE
51-10051FYAPWCPACQ61NLQPEWESFA71EWGEDLEVKV81AKVDVTEQTG91LSGRFIITAL
101-150101PSIYHCKDGE111FRRYVGPRTK121KDFINFVSDK131EWKNIEPISS141WFGPSSVLMT
151-200151MMSALFQLSV161YIRTSHSYFV171HDLGIPAWGS181YLVFAFATVL191SGLLLGLCMI
201-250201FVADCLCPSK211RRKPQQQYAK221KTSPEFSQPL231KKVEEEQEAD241EEDVSEEEAE
251-278251DREGASKATS261QSSIRQRCVG271LPSATDTS
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
56 - - -
Deep-Palm: 0.06
59 - - -
Deep-Palm: 0.03
106 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
liver (26165157)
NSC (31772009)
Brain (35358180)
Deep-Palm: 0.96
198 - - -
Deep-Palm: 0.82
205 - - -
GPS-Palm: 0.96
Deep-Palm: 0.97
207 - - -
GPS-Palm: 0.94
Deep-Palm: 0.97
268 -
brain (39008777)
MLE (39008777)
-
Deep-Palm: 0.09
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.462
6
Liver
Specificity: 0.158
6/6 (100.0%)
2
Raw 264.7
Specificity: 0.053
2/2 (100.0%)
2
Brain
Specificity: 0.053
2/2 (100.0%)
2
Testis
Specificity: 0.053
2/2 (100.0%)
1
NSC
Specificity: 0.026
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.960
24
Brain tissue (Mass)
Specificity: 0.632
24/56 (42.9%)
1
Neural Stem Cells (Mass)
Specificity: 0.026
1/1 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine