Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8VBZ3 Clptm1 Putative lipid scramblase CLPTM1 (Cleft … Mus musculus (Mouse) 664 aa

Protein Details: Q8VBZ3 (Clptm1)

Protein Information
AccessionQ8VBZ3
Protein NamesPutative lipid scramblase CLPTM1 (Cleft lip and palate transmembrane protein 1 homolog) (Thymic epithelial cell surface antigen)
Gene SymbolClptm1
OrganismMus musculus (Mouse)
Length664 aa
IsoformsNo isoforms
Related PMIDs 28526873 34200797 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAAAQEADGA11GSAVVAAGGG21SSGQVTSNGS31IGRDTPAETQ41PQNPPPQPAP
51-10051NAWQVIKGVL61FRIFIIWAIS71SWFRRGPSPQ81DQSGPGGAPR91VASRNLFPKD
101-150101TLMNLHVYIS111EHEHFTDFNA121TSALFWEQHD131LVYGDWTSGE141NSDGCYEHFA
151-200151ELDIPQSVQQ161NGSIYIHVYF171TKSGFHPDPR181QKALYRRLAT191VHMSRMINKY
201-250201KRRRFQKTKN211LLTGETEADP221EMIKRAEDYG231PVEVISHWHP241NITINIVDDH
251-300251TPWVKGSVPP261PLDQYVKFDA271VSGDYYPIIY281FNDYWNLQKD291YYPINESLAS
301-350301LPLRVSFCPL311SLWRWQLYAA321QSTKSPWNFL331GDELYEQSDE341EQDSVKVALL
351-400351ETSPYLLALT361IIVSIVHSVF371EFLAFKNDIQ381FWNSRQSLEG391LSVRSVFFGV
401-450401FQSFVVLLYI411LDNETNFVVQ421VSVFIGVLID431LWKITKVMDV441RLDREHRVAG
451-500451IFPCPTFKDK461STYIESSTKV471YDDMAFRYLS481WILFPLLGCY491AVYSLLYLEH
501-550501KGWYSWVLSM511LYGFLLTFGF521ITMTPQLFIN531YKLKSVAHLP541WRMLTYKALN
551-600551TFIDDLFAFV561IKMPVMYRIG571CLRDDVVFFI581YLYQRWIYRV591DPTRVNEFGM
601-650601SGEDVSAAAS611RAQASTAAGA621LTPAPSTAVS631GEDASTVPKA641TSGACTASQP
651-664651QEAPPKPAED661KKKD
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
145 - - -
Deep-Palm: 0.08
308 SWISSPALM DBPTM CYSMODDB Cleft lip and palate transmembrane protein 1 (CLPTM1)
Liver (28526873)
Brain (35358180)
GPS-Palm: 0.96
Deep-Palm: 0.96
454 SWISSPALM DBPTM CYSMODDB Cleft lip and palate transmembrane protein 1 (CLPTM1)
Liver (28526873)
Brain (35358180)
GPS-Palm: 0.93
Deep-Palm: 0.87
489 - - -
Deep-Palm: 0.56
571 - - -
Deep-Palm: 0.31
645 -
Brain (34200797)
Brain (35358180)
Deep-Palm: 0.91
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
4
Liver
Specificity: 0.138
4/4 (100.0%)
2
Brain
Specificity: 0.069
2/2 (100.0%)
2
Testis
Specificity: 0.069
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
21
Brain tissue (Mass)
Specificity: 0.724
21/56 (37.5%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine