Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8VC19 | Alas1 | 5-aminolevulinate synthase, non-specific, mitochondrial (ALAS-H) … | Mus musculus (Mouse) | 642 aa |
Protein Details: Q8VC19 (Alas1)
Protein Information
| Accession | Q8VC19 |
|---|---|
| Protein Names | 5-aminolevulinate synthase, non-specific, mitochondrial (ALAS-H) (EC 2.3.1.37) (5-aminolevulinic acid synthase 1) (Delta-ALA synthase 1) (Delta-aminolevulinate synthase 1) |
| Gene Symbol | Alas1 |
| Organism | Mus musculus (Mouse) |
| Length | 642 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 34884899 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501METVVRRCPF11LSRVPQAFLQ21KAGKSLLFYA31QNCPKMMEVG41AKPAPRTLST
51-10051SAVHCQQVKE61TPPANEKEKT71AKAAVQQAPD81ESQMAQTPDG91TQLPSGHPSP
101-150101ATSQGSGSKC111PFLAAQLSQT121GSSVFRKASL131ELQEDVQEMH141AVRKEAAQSP
151-200151VPPSLVNVKT161DGEDPSRLLK171NFQDIMRKQR181PERVSHLLQD191NLPKSVSTFQ
201-250201YDHFFEKKID211EKKNDHTYRV221FKTVNRRAQI231FPMADDYTDS241LITKKQVSVW
251-300251CSNDYLGMSR261HPRVCGAVME271TVKQHGAGAG281GTRNISGTSK291FHVELEQALA
301-350301DLHGKDAALL311FSSCFVANDS321TLFTLAKMMP331GCEIYSDSGN341HASMIQGIRN
351-400351SRVPKYIFRH361NDVNHLRELL371QRSDPSVPKI381VAFETVHSMD391GAVCPLEELC
401-450401DVAHEFGAIT411FVDEVHAVGL421YGARGGGIGD431RDGVMPKMDI441ISGTLGKAFG
451-500451CVGGYIASTS461LLIDTVRSYA471AGFIFTTSLP481PMLLAGALES491VRILKSSEGR
501-550501ALRRQHQRNV511KLLRQMLMDA521GLPVIHCPSH531IIPVRVADAA541KNTEICDELM
551-600551TRHNIYVQAI561NYPTVPRGEE571LLRIAPTPHH581TPQMMNFFVE591KLLVTWKRVG
601-642601LELKPHSSAE611CNFCRRPLHF621EVMSEREKAY631FSGMSKMVSA641QA
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 8 | 5-aminolevulinate synthase presequence | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.11
|
|
| 33 | 5-aminolevulinate synthase presequence | - | - |
Deep-Palm: 0.88
|
|
| 55 | - | - | - |
Deep-Palm: 0.97
|
|
| 110 | - | - | - |
Deep-Palm: 0.79
|
|
| 251 | - | - | - |
Deep-Palm: 0.35
|
|
| 265 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
| - |
GPS-Palm: 0.93
Deep-Palm: 0.73
|
| 314 | - | - | - |
Deep-Palm: 0.93
|
|
| 332 | - | - | - |
Deep-Palm: 0.42
|
|
| 394 | - | - | - |
Deep-Palm: 0.62
|
|
| 400 | - | - | - |
Deep-Palm: 0.55
|
|
| 451 | - | - | - |
Deep-Palm: 0.93
|
|
| 527 | - | - | - |
Deep-Palm: 0.92
|
|
| 546 | - | - | - |
Deep-Palm: 0.61
|
|
| 611 | - | - | - |
Deep-Palm: 0.87
|
|
| 614 | - | - | - |
Deep-Palm: 0.76
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Liver
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.