Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8VCF0 Mavs Mitochondrial antiviral-signaling protein (MAVS) (CARD … Mus musculus (Mouse) 503 aa

Protein Details: Q8VCF0 (Mavs)

Protein Information
AccessionQ8VCF0
Protein NamesMitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Virus-induced-signaling adapter) (VISA)
Gene SymbolMavs
OrganismMus musculus (Mouse)
Length503 aa
IsoformsNo isoforms
Related PMIDs 28526873 34200797 34884899 35477839 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MTFAEDKTYK11YIRDNHSKFC21CVDVLEILPY31LSCLTASDQD41RLRASYRQIG
51-10051NRDTLWGLFN61NLQRRPGWVE71VFIRALQICE81LPGLADQVTR91VYQSYLPPGT
101-150101SLRSLEPLQL111PDFPAAVSGP121SAFAPGHNIP131DHGLRETPSC141PKPVQDTQPP
151-200151ESPVENSEQL161LQTNSGAVAR171MSGGSLIPSP181NQQALSPQPS191REHQEQEPEL
201-250201GGAHAANVAS211VPIATYGPVS221PTVSFQPLPR231TALRTNLLSG241VTVSALSADT
251-300251SLSSSSTGSA261FAKGAGDQAK271AATCFSTTLT281NSVTTSSVPS291PRLVPVKTMS
301-350301SKLPLSSKST311AAMTSTVLTN321TAPSKLPSNS331VYAGTVPSRV341PASVAKAPAN
351-400351TIPPERNSKQ361AKETPEGPAT371KVTTGGNQTG381PNSSIRSLHS391GPEMSKPGVL
401-450401VSQLDEPFSA411CSVDLAISPS421SSLVSEPNHG431PEENEYSSFR441IQVDESPSAD
451-500451LLGSPEPLAT461QQPQEEEEHC471ASSMPWAKWL481GATSALLAVF491LAVMLYRSRR
501-503501LAQ
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
20 Caspase recruitment domain Death-like domain superfamily - -
Deep-Palm: 0.25
21 Caspase recruitment domain Death-like domain superfamily - -
Deep-Palm: 0.34
33 Caspase recruitment domain Death-like domain superfamily - -
Deep-Palm: 0.83
79 SWISSPALM DBPTM CYSMODDB Caspase recruitment domain
Liver (28526873)
liver (26165157)
Forebrain (28680068)
-
Deep-Palm: 0.94
140 -
Brain (34200797)
-
Deep-Palm: 0.27
274 - - -
Deep-Palm: 0.95
411 - - -
Deep-Palm: 0.97
470 - - -
Deep-Palm: 0.45
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.625
5
Liver
Specificity: 0.625
5/5 (100.0%)
2
Testis
Specificity: 0.250
2/2 (100.0%)
1
Brain
Specificity: 0.125
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine