Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8VCN5 Cth Cystathionine gamma-lyase (CGL) (CSE) (EC … Mus musculus (Mouse) 398 aa

Protein Details: Q8VCN5 (Cth)

Protein Information
AccessionQ8VCN5
Protein NamesCystathionine gamma-lyase (CGL) (CSE) (EC 4.4.1.1) (Cysteine desulfhydrase) (Cysteine-protein sulfhydrase) (Gamma-cystathionase) (Homocysteine desulfhydrase) (EC 4.4.1.2)
Gene SymbolCth
OrganismMus musculus (Mouse)
Length398 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MQKDASLSGF11LPSFQHFATQ21AIHVGQEPEQ31WNSRAVVLPI41SLATTFKQDF
51-10051PGQSSGFEYS61RSGNPTRNCL71EKAVAALDGA81KHSLAFASGL91AATITITHLL
101-150101KAGDEIICMD111EVYGGTNRYF121RRVASEFGLK131ISFVDCSKTK141LLEAAITPQT
151-200151KLVWIETPTN161PTLKLADIGA171CAQIVHKRGD181IILVVDNTFM191SAYFQRPLAL
201-250201GADICMCSAT211KYMNGHSDVV221MGLVSVNSDD231LNSRLRFLQN241SLGAVPSPFD
251-300251CYLCCRGLKT261LQVRMEKHFK271NGMAVARFLE281TNPRVEKVVY291PGLPSHPQHE
301-350301LAKRQCSGCP311GMVSFYIKGA321LQHAKAFLKN331LKLFTLAESL341GGYESLAELP
351-398351AIMTHASVPE361KDRATLGIND371TLIRLSVGLE381DEQDLLEDLD391RALKAAHP
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
69 - - -
Deep-Palm: 0.98
108 - - -
Deep-Palm: 0.88
136 SWISSPALM DBPTM CYSMODDB Cys/Met metabolism PLP-dependent enzyme
Liver (28526873)
-
GPS-Palm: 0.94
Deep-Palm: 0.97
171 SWISSPALM DBPTM CYSMODDB Cys/Met metabolism PLP-dependent enzyme
liver (26165157)
Liver (28526873)
NSC (31772009)
Deep-Palm: 0.96
205 - - -
Deep-Palm: 0.71
207 - - -
Deep-Palm: 0.83
251 - - -
GPS-Palm: 0.93
Deep-Palm: 0.96
254 - - -
GPS-Palm: 0.89
Deep-Palm: 0.95
255 - - -
GPS-Palm: 0.93
Deep-Palm: 0.95
306 - - -
Deep-Palm: 0.77
309 - - -
Deep-Palm: 0.54
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
6
Liver
Specificity: 1.000
6/6 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine