Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8WTS1 | ABHD5 | 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (EC 2.3.1.51) … | Homo sapiens (Human) | 349 aa |
Protein Details: Q8WTS1 (ABHD5)
Protein Information
| Accession | Q8WTS1 |
|---|---|
| Protein Names | 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (EC 2.3.1.51) (Abhydrolase domain-containing protein 5) (Lipid droplet-binding protein CGI-58) |
| Gene Symbol | ABHD5 |
| Organism | Homo sapiens (Human) |
| Length | 349 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAAEEEEVDS11ADTGERSGWL21TGWLPTWCPT31SISHLKEAEE41KMLKCVPCTY
51-10051KKEPVRISNG61NKIWTLKFSH71NISNKTPLVL81LHGFGGGLGL91WALNFGDLCT
101-150101NRPVYAFDLL111GFGRSSRPRF121DSDAEEVENQ131FVESIEEWRC141ALGLDKMILL
151-200151GHNLGGFLAA161AYSLKYPSRV171NHLILVEPWG181FPERPDLADQ191DRPIPVWIRA
201-250201LGAALTPFNP211LAGLRIAGPF221GLSLVQRLRP231DFKRKYSSMF241EDDTVTEYIY
251-300251HCNVQTPSGE261TAFKNMTIPY271GWAKRPMLQR281IGKMHPDIPV291SVIFGARSCI
301-349301DGNSGTSIQS311LRPHSYVKTI321AILGAGHYVY331ADQPEEFNQK341VKEICDTVD
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 28 | - | - | - |
GPS-Palm: 0.66
Deep-Palm: 0.92
|
|
| 45 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.92
|
|
| 48 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.92
|
|
| 99 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.98
|
|
| 140 | - | - | - |
Deep-Palm: 0.93
|
|
| 252 | - | - | - |
Deep-Palm: 0.05
|
|
| 299 | - | - | - |
Deep-Palm: 0.62
|
|
| 345 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.01
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 56 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 330 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 345 | C → C | 0.001887 | SNP | Silent | UCEC |