Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8WUY9 | DEPDC1B | DEP domain-containing protein 1B (HBV … | Homo sapiens (Human) | 529 aa |
Protein Details: Q8WUY9 (DEPDC1B)
Protein Information
| Accession | Q8WUY9 |
|---|---|
| Protein Names | DEP domain-containing protein 1B (HBV X-transactivated gene 8 protein) (HBV XAg-transactivated protein 8) |
| Gene Symbol | DEPDC1B |
| Organism | Homo sapiens (Human) |
| Length | 529 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MEHRIVGPGP11YRATRLWNET21VELFRAKMPL31RKHRCRFKSY41EHCFTAAEAV
51-10051DWLHELLRCS61QNFGPEVTRK71QTVQLLKKFL81KNHVIEDIKG91KWGEEDFEDN
101-150101RHLYRFPPSS111PLKPYPKKPP121NQKDVIKFPE131WNDLPPGTSQ141ENIPVRPVVM
151-200151NSEMWYKRHS161IAIGEVPACR171LVHRRQLTEA181NVEEIWKSMT191LSYLQKILGL
201-250201DSLEEVLDVK211LVNSKFIIHN221VYSVSKQGVV231ILDDKSKELP241HWVLSAMKCL
251-300251ANWPNCSDLK261QPMYLGFEKD271VFKTIADYYG281HLKEPLLTFH291LFDAFVSVLG
301-350301LLQKEKVAVE311AFQICCLLLP321PENRRKLQLL331MRMMARICLN341KEMPPLCDGF
351-400351GTRTLMVQTF361SRCILCSKDE371VDLDELLAAR381LVTFLMDNYQ391EILKVPLALQ
401-450401TSIEERVAHL411RRVQIKYPGA421DMDITLSAPS431FCRQISPEEF441EYQRSYGSQE
451-500451PLAALLEEVI461TDAKLSNKEK471KKKLKQFQKS481YPEVYQERFP491TPESAALLFP
501-529501EKPKPKPQLL511MWALKKPFQP521FQRTRSFRM
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 35 | DEP domain DEP DOMAIN-CONTAINING Winged helix-like DNA-binding domain superfamily Winged helix DNA-binding domain superfamily | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.53
|
|
| 43 | DEP DOMAIN-CONTAINING Winged helix-like DNA-binding domain superfamily | - | - |
Deep-Palm: 0.53
|
|
| 59 | - | - | - |
Deep-Palm: 0.88
|
|
| 169 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.84
|
|
| 249 | - | - | - |
Deep-Palm: 0.39
|
|
| 256 | - | - | - |
Deep-Palm: 0.27
|
|
| 315 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.97
|
|
| 316 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.97
|
|
| 338 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.82
|
|
| 347 | - | - | - |
GPS-Palm: 0.76
Deep-Palm: 0.52
|
|
| 363 | - | - | - |
Deep-Palm: 0.93
|
|
| 366 | - | - | - |
Deep-Palm: 0.97
|
|
| 432 | - |
HeLa
(37611173)
| - |
Deep-Palm: 0.39
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 34 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 64 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 109 | S → _S110insKCNALE | 0.001887 | INS | In Frame Ins | UCEC |
| 158 | R → C | 0.002020 | SNP | Missense Mutation | PRAD |
| 292 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 406 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |