Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8WV19 | SFT2D1; C6orf83 | Vesicle transport protein SFT2A (SFT2 … | Homo sapiens (Human) | 159 aa |
Protein Details: Q8WV19 (SFT2D1)
Protein Information
| Accession | Q8WV19 |
|---|---|
| Protein Names | Vesicle transport protein SFT2A (SFT2 domain-containing protein 1) (pRGR1) |
| Gene Symbol | SFT2D1; C6orf83 |
| Organism | Homo sapiens (Human) |
| Length | 159 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 29575903 29733200 31251020 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
33
LNCaP cells
Specificity: 0.750
33/46 (71.7%)
6
Jurkat T cells
Specificity: 0.136
6/25 (24.0%)
4
HAP1 cells
Specificity: 0.091
4/10 (40.0%)
1
Cerebral cortex
Specificity: 0.023
1/4 (25.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MEKLRRVLSG11QDDEEQGLTA21QVLDASSLSF31NTRLKWFAIC41FVCGVFFSIL
51-10051GTGLLWLPGG61IKLFAVFYTL71GNLAALASTC81FLMGPVKQLK91KMFEATRLLA
101-150101TIVMLLCFIF111TLCAALWWHK121KGLAVLFCIL131QFLSMTWYSL141SYIPYARDAV
151-159151IKCCSSLLS
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 40 | Prediction (Medium) | - | - |
| 43 | Prediction (Medium) | - | - |
| 80 | Prediction (Medium) | - | - |
| 113 | Prediction (Medium) | - | - |
| 128 | Prediction (Low) | - | - |
| 153 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) | - | 29575903 |
| 154 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) | - | 29575903 |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 128 | C → C | 0.002288 | SNP | Silent | STAD |
| 154 | C → S | 0.001764 | SNP | Missense Mutation | LUAD |
| 153* | C → ? | 0.001887 | SNP | Nonsense Mutation | UCEC |