Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8WV19 | SFT2D1 | Vesicle transport protein SFT2A (SFT2 … | Homo sapiens (Human) | 159 aa |
Protein Details: Q8WV19 (SFT2D1)
Protein Information
| Accession | Q8WV19 |
|---|---|
| Protein Names | Vesicle transport protein SFT2A (SFT2 domain-containing protein 1) (pRGR1) |
| Gene Symbol | SFT2D1 |
| Organism | Homo sapiens (Human) |
| Length | 159 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 29733200 31251020 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MEKLRRVLSG11QDDEEQGLTA21QVLDASSLSF31NTRLKWFAIC41FVCGVFFSIL
51-10051GTGLLWLPGG61IKLFAVFYTL71GNLAALASTC81FLMGPVKQLK91KMFEATRLLA
101-150101TIVMLLCFIF111TLCAALWWHK121KGLAVLFCIL131QFLSMTWYSL141SYIPYARDAV
151-159151IKCCSSLLS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 40 | Vesicle transport protein SFT2 | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.64
|
|
| 43 | Vesicle transport protein SFT2 | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.44
|
|
| 80 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.93
|
|
| 107 | - | - | - |
Deep-Palm: 0.35
|
|
| 113 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.87
|
|
| 128 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.29
|
|
| 153 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
| - |
GPS-Palm: 0.95
Deep-Palm: 0.02
|
| 154 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
| - |
GPS-Palm: 0.97
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
3
LNCaP
Specificity: 0.429
3/3 (100.0%)
2
Jurkat T cell
Specificity: 0.286
2/2 (100.0%)
1
HAP1 cell
Specificity: 0.143
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 0.143
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 128 | C → C | 0.002288 | SNP | Silent | STAD |
| 154 | C → S | 0.001764 | SNP | Missense Mutation | LUAD |
| 153* | C → ? | 0.001887 | SNP | Nonsense Mutation | UCEC |