Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8WXI4-2 | ACOT11 | Acyl-coenzyme A thioesterase 11 (Acyl-CoA … | Homo sapiens (Human) | 594 aa |
Protein Details: Q8WXI4-2 (ACOT11)
Protein Information
| Accession | Q8WXI4-2 |
|---|---|
| Protein Names | Acyl-coenzyme A thioesterase 11 (Acyl-CoA thioesterase 11) (EC 3.1.2.-) (Acyl-CoA thioester hydrolase 11) (Adipose-associated thioesterase) (Brown fat-inducible thioesterase) (BFIT) (Palmitoyl-coenzyme A thioesterase) (EC 3.1.2.2) |
| Gene Symbol | ACOT11 |
| Organism | Homo sapiens (Human) |
| Length | 594 aa |
| Isoforms | |
| Related PMIDs | 31251020 33636221 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MIQNVGNHLR11RGLASVFSNR21TSRKSALRAG31NDSAMADGEG41YRNPTEVQMS
51-10051QLVLPCHTNQ61RGELSVGQLL71KWIDTTACLS81AERHAGCPCV91TASMDDIYFE
101-150101HTISVGQVVN111IKAKVNRAFN121SSMEVGIQVA131SEDLCSEKQW141NVCKALATFV
151-200151ARREITKVKL161KQITPRTEEE171KMEHSVAAER181RRMRLVYADT191IKDLLANCAI
201-250201QGDLESRDCS211RMVPAEKTRV221ESVELVLPPH231ANHQGNTFGG241QIMAWMENVA
251-300251TIAASRLCRA261HPTLKAIEMF271HFRGPSQVGD281RLVLKAIVNN291AFKHSMEVGV
301-350301CVEAYRQEAE311THRRHINSAF321MTFVVLDADD331QPQLLPWIRP341QPGDGERRYR
351-400351EASARKKIRL361DRKYIVSCKQ371TEVPLSVPWD381PSNQVYLSYN391NVSSLKMLVA
401-450401KDNWVLSSEI411SQVRLYTLED421DKFLSFHMEM431VVHVDAAQAF441LLLSDLRQRP
451-500451EWDKHYRSVE461LVQQVDEDDA471IYHVTSPALG481GHTKPQDFVI491LASRRKPCDN
501-550501GDPYVIALRS511VTLPTHRETP521EYRRGETLCS531GFCLWREGDQ541LTKVSYYNQA
551-594551TPGVLNYVTT561NVAGLSSEFY571TTFKACEQFL581LDNRNDLAPS591LQTL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 56 | - | - | - |
Deep-Palm: 0.98
|
|
| 78 | - | - | - |
Deep-Palm: 0.96
|
|
| 87 | - | - | - |
Deep-Palm: 0.10
|
|
| 89 | - | - | - |
Deep-Palm: 0.13
|
|
| 135 | - | - | - |
Deep-Palm: 0.77
|
|
| 143 | - | - | - |
Deep-Palm: 0.92
|
|
| 198 | - | - | - |
Deep-Palm: 0.92
|
|
| 209 | - | - | - |
Deep-Palm: 0.89
|
|
| 258 | - | - | - |
Deep-Palm: 0.66
|
|
| 301 | - | - | - |
Deep-Palm: 0.36
|
|
| 368 | - | - | - |
Deep-Palm: 0.94
|
|
| 498 | - | - | - |
Deep-Palm: 0.87
|
|
| 529 | - | - | - |
Deep-Palm: 0.85
|
|
| 533 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.79
|
|
| 544 | - | - | - |
Deep-Palm: 0.84
|
|
| 545 | - | - | - |
Deep-Palm: 0.89
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
1
LNCaP
Specificity: 0.500
1/1 (100.0%)
1
heart
Specificity: 0.500
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 121 | S → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 235 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 306 | R → C | 0.002545 | SNP | Missense Mutation | GBM |
| 306 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 524 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 578 | N → delinsKC | 0.003460 | INS | In Frame Ins | CESC |