Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q91W90 | Txndc5 | Thioredoxin domain-containing protein 5 (EC … | Mus musculus (Mouse) | 417 aa |
Protein Details: Q91W90 (Txndc5)
Protein Information
| Accession | Q91W90 |
|---|---|
| Protein Names | Thioredoxin domain-containing protein 5 (EC 1.8.4.-) (EC 5.3.4.1) (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Plasma cell-specific thioredoxin-related protein) (PC-TRP) (Thioredoxin-like protein p46) |
| Gene Symbol | Txndc5 |
| Organism | Mus musculus (Mouse) |
| Length | 417 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MPPRPGRLLQ11PLAGLPALAT21LLLLLGARKG31ARAQEVEADS41GVEQDPHAKH
51-10051LYTADMFTHG61IQSAAHFVMF71FAPWCGHCQR81LQPTWNDLGD91KYNSMEDAKV
101-150101YVAKVDCTAD111SDVCSAQGVR121GYPTLKFFKP131GQEAVKYQGP141RDFETLENWM
151-200151LQTLNEEPAT161PEPEAEPPRA171PELKQGLYEL181SANNFELHVS191QGNHFIKFFA
201-250201PWCGHCKALA211PTWEQLALGL221EHSETVKIGK231VDCTQHYAVC241SEHQVRGYPT
251-300251LLWFRDGKKV261DQYKGKRDLE271SLRDYVQSQL281QGSEAAPETV291EPSEAPVMAA
301-350301EPTGDKGTVL311ALTEKSFEDT321IAQGITFVKF331YAPWCGHCKN341LAPTWEELSK
351-400351KEFPGLSDVT361IAEVDCTAER371NVCSKYSVRG381YPTLLLFRGG391EKVGEHNGGR
401-417401DLDSLHSFVL411RQAKDEL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 75 | - | - | - |
Deep-Palm: 0.04
|
|
| 78 | - | - | - |
Deep-Palm: 0.04
|
|
| 107 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.67
|
|
| 114 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.94
|
|
| 203 | - | - | - |
Deep-Palm: 0.28
|
|
| 206 | - | - | - |
Deep-Palm: 0.61
|
|
| 233 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.77
|
|
| 240 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.82
|
|
| 335 | - | - | - |
Deep-Palm: 0.28
|
|
| 338 | - | - | - |
Deep-Palm: 0.40
|
|
| 366 | - |
brain
(39008777)
MLE
(39008777)
|
Brain
(35358180)
|
Deep-Palm: 0.94
|
|
| 373 | SWISSPALM DBPTM CYSMODDB | Thioredoxin | - | - |
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.556
5
Liver
Specificity: 0.185
5/5 (100.0%)
2
Brain
Specificity: 0.074
2/2 (100.0%)
2
Testis
Specificity: 0.074
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
18
Brain tissue (Mass)
Specificity: 0.667
18/56 (32.1%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.