Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q91WC0 Setd3 Actin-histidine N-methyltransferase (EC 2.1.1.85) (Endothelial … Mus musculus (Mouse) 594 aa

Protein Details: Q91WC0 (Setd3)

Protein Information
AccessionQ91WC0
Protein NamesActin-histidine N-methyltransferase (EC 2.1.1.85) (Endothelial differentiation inhibitory protein D10) (Protein-L-histidine N-tele-methyltransferase) (SET domain-containing protein 3)
Gene SymbolSetd3
OrganismMus musculus (Mouse)
Length594 aa
IsoformsNo isoforms
Related PMIDs 34884899 35477839
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MGKKSRVKTQ11KSGTGATATV21SPKEILNLTS31ELLQKCSSPA41PSPGKEWEEY
51-10051TQIRALVEKI61RKKQKGLSVT71FDGKREDYFP81DLMKWASENG91ASVEGFEMVN
101-150101FKEEGFGLRA111TRDIKAEELF121LWVPRKLLMT131VESAKNSVLG141PLYSQDRILQ
151-200151AMGNIALAFH161LLCERASPNS171FWQPYIQTLP181SEYDTPLYFE191EEEVRCLQST
201-250201QAIHDVFSQY211KNTARQYAYF221YKVIQTHPHA231NKLPLKESFT241YEDYRWAVSS
251-300251VMTRQNQIPT261EDGSRVTLAL271IPLWDMCNHT281NGLITTGYNL291EDDRCECVAL
301-350301QDFQAGDQIY311IFYGTRSNAE321FVIHSGFFFD331NNSHDRVKIK341LGVSKSDRLY
351-400351AMKAEVLARA361GIPTSSVFAL371HSTEPPISAQ381LLAFLRVFCM391TEEELKEHLL
401-450401GDSAIDRIFT411LGNAEFPVSW421DNEVKLWTFL431EDRASLLLKT441YKTTIEEDKI
451-500451VLKNPDLSVR461ATMAIKLRLG471EKEILEKAVK481SAAVNREYYR491KHMEERAPLP
501-550501RYEESDLGLL511EGGVGDSRLP521LVLRKLEEEA531GVQESLSLTE541TVSKVKAAEN
551-594551GLVNGENLIP561NGTRSENESL571SPEESENVTG581EESSGSMAKV591KERL
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
36 set domain protein methyltransferase, domain 1 - -
Deep-Palm: 0.96
163 - - -
Deep-Palm: 0.52
196 - - -
Deep-Palm: 0.24
277 - - -
Deep-Palm: 0.17
295 - - -
Deep-Palm: 0.15
297 - - -
Deep-Palm: 0.19
389 - - -
Deep-Palm: 0.96
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
Testis
Specificity: 0.667
2/2 (100.0%)
1
Liver
Specificity: 0.333
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine