Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q91WG8 | Gne | Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (UDP-GlcNAc-2-epimerase/ManAc … | Mus musculus (Mouse) | 722 aa |
Protein Details: Q91WG8 (Gne)
Protein Information
| Accession | Q91WG8 |
|---|---|
| Protein Names | Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (UDP-GlcNAc-2-epimerase/ManAc kinase) [Includes: UDP-N-acetylglucosamine 2-epimerase (hydrolyzing) (EC 3.2.1.183) (UDP-GlcNAc-2-epimerase) (Uridine diphosphate-N-acetylglucosamine-2-epimerase); N-acetylmannosamine kinase (EC 2.7.1.60) (ManAc kinase)] |
| Gene Symbol | Gne |
| Organism | Mus musculus (Mouse) |
| Length | 722 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 34884899 37925639 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MEKNGNNRKL11RVCVATCNRA21DYSKLAPIMF31GIKTEPAFFE41LDVVVLGSHL
51-10051IDDYGNTYRM61IEQDDFDINT71RLHTIVRGED81EAAMVESVGL91ALVKLPDVLN
101-150101RLKPDIMIVH111GDRFDALALA121TSAALMNIRI131LHIEGGEVSG141TIDDSIRHAI
151-200151TKLAHYHVCC161TRSAEQHLIS171MCEDHDRILL181AGCPSYDKLL191SAKNKDYMSI
201-250201IRMWLGDDVK211CKDYIVALQH221PVTTDIKHSI231KMFELTLDAL241ISFNKRTLVL
251-300251FPNIDAGSKE261MVRVMRKKGI271EHHPNFRAVK281HVPFDQFIQL291VAHAGCMIGN
301-350301SSCGVREVGA311FGTPVINLGT321RQIGRETGEN331VLHVRDADTQ341DKILQALHLQ
351-400351FGKQYPCSKI361YGDGNAVPRI371LKFLKSIDLQ381EPLQKKFCFP391PVKENISQDI
401-450401DHILETLSAL411AVDLGGTNLR421VAIVSMKGEI431VKKYTQFNPK441TYEERISLIL
451-500451QMCVEAAAEA461VKLNCRILGV471GISTGGRVNP481QEGVVLHSTK491LIQEWNSVDL
501-550501RTPLSDTLHL511PVWVDNDGNC521AAMAERKFGQ531GKGQENFVTL541ITGTGIGGGI
551-600551IHQHELIHGS561SFCAAELGHL571VVSLDGPDCS581CGSHGCIEAY591ASGMALQREA
601-650601KKLHDEDLLL611VEGMSVPKDE621AVGALHLIQA631AKLGNVKAQS641ILRTAGTALG
651-700651LGVVNILHTM661NPSLVILSGV671LASHYIHIVK681DVIRQQALSS691VQDVDVVVSD
701-722701LVDPALLGAA711SMVLDYTTRR721IH
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 13 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.31
|
|
| 17 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.86
|
|
| 159 | - | - | - |
Deep-Palm: 0.22
|
|
| 160 | - | - | - |
Deep-Palm: 0.06
|
|
| 172 | SWISSPALM DBPTM CYSMODDB | UDP-N-acetylglucosamine 2-epimerase |
Liver
(28526873)
| - |
Deep-Palm: 0.11
|
| 183 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
| - |
GPS-Palm: 0.92
Deep-Palm: 0.79
|
| 211 | - | - | - |
Deep-Palm: 0.11
|
|
| 296 | - | - | - |
Deep-Palm: 0.77
|
|
| 303 | - | - | - |
Deep-Palm: 0.94
|
|
| 357 | - | - | - |
Deep-Palm: 0.85
|
|
| 388 | - | - | - |
Deep-Palm: 0.80
|
|
| 453 | - | - | - |
Deep-Palm: 0.81
|
|
| 465 | - | - | - |
Deep-Palm: 0.90
|
|
| 520 | SWISSPALM DBPTM CYSMODDB | ROK family |
Liver
(28526873)
| - |
Deep-Palm: 0.83
|
| 563 | - | - | - |
Deep-Palm: 0.79
|
|
| 579 | - | - | - |
Deep-Palm: 0.93
|
|
| 581 | - | - | - |
Deep-Palm: 0.83
|
|
| 586 | - | - | - |
Deep-Palm: 0.56
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
5
Liver
Specificity: 1.000
5/5 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.