Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q91X83 Mat1a S-adenosylmethionine synthase isoform type-1 (AdoMet … Mus musculus (Mouse) 396 aa

Protein Details: Q91X83 (Mat1a)

Protein Information
AccessionQ91X83
Protein NamesS-adenosylmethionine synthase isoform type-1 (AdoMet synthase 1) (EC 2.5.1.6) (Methionine adenosyltransferase 1) (MAT 1)
Gene SymbolMat1a
OrganismMus musculus (Mouse)
Length396 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MNGPVDGLCD11HSLSEEGAFM21FTSESVGEGH31PDKICDQISD41AVLDAHLKQD
51-10051PNAKVACETV61CKTGMVLLCG71EITSVAMVDY81QRVVRDTIKH91IGYDDSAKGF
101-150101DFKTCNVLVA111LEQQSPDIAQ121CVHLDRNEED131VGAGDQGLMF141GYATDETEEC
151-200151MPLTIVLAHK161LNTRIADLRR171SGVLPWLRPD181SKTQVTVQYM191QDNGAVIPVR
201-250201IHTIVISVQH211NEDITLEAMQ221EALKEQVIKA231VVPAKYLDED241TVYHLQPSGR
251-300251FVIGGPQGDA261GVTGRKIIVD271TYGGWGAHGG281GAFSGKDYTK291VDRSAAYAAR
301-350301WVAKSLVKAG311LCRRVLVQVS321YAIGVAEPLS331ISIFTYGTSN341KTERELLEVV
351-396351NKNFDLRPGV361IVRDLDLKKP371IYQKTACYGH381FGRSEFPWEV391PKKLVF
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
9 - - -
Deep-Palm: 0.02
35 SWISSPALM DBPTM CYSMODDB S-adenosylmethionine synthetase S-adenosylmethionine synthetase, N-terminal S-adenosylmethionine synthetase superfamily S-adenosylmethionine synthetase N-terminal domain
Liver (28526873)
-
Deep-Palm: 0.75
57 SWISSPALM DBPTM CYSMODDB S-adenosylmethionine synthetase N-terminal domain
Liver (28526873)
-
Deep-Palm: 0.95
61 SWISSPALM DBPTM CYSMODDB S-adenosylmethionine synthetase N-terminal domain
Liver (28526873)
-
Deep-Palm: 0.94
69 - - -
Deep-Palm: 0.81
105 SWISSPALM DBPTM CYSMODDB S-adenosylmethionine synthetase N-terminal domain
Liver (28526873)
Liver (37925639)
Deep-Palm: 0.82
121 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Liver (37925639)
Deep-Palm: 0.82
150 SWISSPALM DBPTM CYSMODDB S-adenosylmethionine synthetase central domain
Liver (28526873)
Liver (34884899)
Deep-Palm: 0.62
312 - - -
Deep-Palm: 0.95
377 SWISSPALM DBPTM CYSMODDB S-adenosylmethionine synthetase C-terminal domain
liver (26165157)
Liver (28526873)
Liver (37925639)
Deep-Palm: 0.88
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
6
Liver
Specificity: 0.545
6/6 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
5
Liver tissue (Mass)
Specificity: 0.455
5/8 (62.5%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine