Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q91XH5 Spr Sepiapterin reductase (EC 1.1.1.153) Mus musculus (Mouse) 262 aa

Protein Details: Q91XH5 (Spr)

Protein Information
AccessionQ91XH5
Protein NamesSepiapterin reductase (EC 1.1.1.153)
Gene SymbolSpr
OrganismMus musculus (Mouse)
Length262 aa
IsoformsNo isoforms
Related PMIDs 35477839 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MEAGGLGCAV11CVLTGASRGF21GRALAPQLAR31LLSPGSVMLV41SARSESMLRQ
51-10051LKEELGAQQP61DLKVVLAAAD71LGTEAGVQRL81LSAVRELPRP91EGLQRLLLIN
101-150101NAATLGDVSK111GFLNVNDLAE121VNNYWALNLT131SMLCLTSGTL141NAFQDSPGLS
151-200151KTVVNISSLC161ALQPYKGWGL171YCAGKAARDM181LYQVLAAEEP191SVRVLSYAPG
201-250201PLDNDMQQLA211RETSKDPELR221SKLQKLKSDG231ALVDCGTSAQ241KLLGLLQKDT
251-262251FQSGAHVDFY261DC
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
8 NAD(P)-binding domain superfamily -
Liver (37925639)
Brain (35358180)
GPS-Palm: 0.84
Deep-Palm: 0.21
11 NAD(P)-binding domain superfamily -
Liver (37925639)
Brain (35358180)
GPS-Palm: 0.67
Deep-Palm: 0.79
134 - - -
GPS-Palm: 0.76
Deep-Palm: 0.82
160 SWISSPALM DBPTM CYSMODDB - -
Brain (35358180)
GPS-Palm: 0.92
Deep-Palm: 0.97
172 - - -
GPS-Palm: 0.92
Deep-Palm: 0.97
235 - -
Brain (35358180)
GPS-Palm: 0.92
Deep-Palm: 0.98
262 - - -
GPS-Palm: 0.93
Deep-Palm: 0.01
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Testis
Specificity: 0.067
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.857
24
Brain tissue (Mass)
Specificity: 0.800
24/56 (42.9%)
4
Liver tissue (Mass)
Specificity: 0.133
4/8 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine