Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q91Y47 | F11 | Coagulation factor XI (FXI) (EC … | Mus musculus (Mouse) | 624 aa |
Protein Details: Q91Y47 (F11)
Protein Information
| Accession | Q91Y47 |
|---|---|
| Protein Names | Coagulation factor XI (FXI) (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) [Cleaved into: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain] |
| Gene Symbol | F11 |
| Organism | Mus musculus (Mouse) |
| Length | 624 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26165157 37925639 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
6
Liver tissue
Specificity: 1.000
6/19 (31.6%)
0
Brain tissue
Specificity: 0.000
0/12 (0.0%)
0
Macrophage Raw 264.7
Specificity: 0.000
0/2 (0.0%)
0
Neural Stem Cells
Specificity: 0.000
0/3 (0.0%)
0
Testis
Specificity: 0.000
0/2 (0.0%)
0
Liver membrane
Specificity: 0.000
0/6 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MTSLHQVLYF11IFFASVSSEC21VTKVFKDISF31QGGDLSTVFT41PSATYCRLVC
51-10051THHPRCLLFT61FMAESSSDDP71TKWFACILKD81SVTEILPMVN91MTGAISGYSF
101-150101KQCPQQLSTC111SKDVYVNLDM121KGMNYNSSVV131KNARECQERC141TDDAHCQFFT
151-200151YATGYFPSVD161HRKMCLLKYT171RTGTPTTITK181LNGVVSGFSL191KSCGLSNLAC
201-250201IRDIFPNTVL211ADLNIDSVVA221PDAFVCRRIC231THHPTCLFFT241FFSQAWPKES
251-300251QRHLCLLKTS261ESGLPSTRIT271KSHALSGFSL281QHCRHSVPVF291CHPSFYNDTD
301-350301FLGEELDIVD311VKGQETCQKT321CTNNARCQFF331TYYPSHRLCN341ERNRRGRCYL
351-400351KLSSNGSPTR361ILHGRGGISG371YSLRLCKMDN381VCTTKINPRV391VGGAASVHGE
401-450401WPWQVTLHIS411QGHLCGGSII421GNQWILTAAH431CFSGIETPKK441LRVYGGIVNQ
451-500451SEINEGTAFF461RVQEMIIHDQ471YTTAESGYDI481ALLKLESAMN491YTDFQRPICL
501-550501PSKGDRNAVH511TECWVTGWGY521TALRGEVQST531LQKAKVPLVS541NEECQTRYRR
551-600551HKITNKMICA561GYKEGGKDTC571KGDSGGPLSC581KYNGVWHLVG591ITSWGEGCGQ
601-624601KERPGVYTNV611AKYVDWILEK621TQTV
Palmitoylation Sites Details
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 50 | C → C | 0.001887 | SNP | Silent | UCEC |
| 129 | V → Cfs*14 | 0.002294 | DEL | Frame Shift Del | OV |
| 136 | C → W | 0.001764 | SNP | Missense Mutation | LUAD |
| 165 | C → C | 0.001887 | SNP | Silent | UCEC |
| 268 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 326 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 327 | C → Y | 0.002020 | SNP | Missense Mutation | PRAD |
| 346 | C → Y | 0.002427 | SNP | Missense Mutation | BLCA |
| 396 | R → C | 0.007299 | SNP | Missense Mutation | READ |
| 503 | S → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 514 | C → C | 0.001887 | SNP | Silent | UCEC |
| 571 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 599 | C → F | 0.002141 | SNP | Missense Mutation | SKCM |
| 617 | W → C | 0.001887 | SNP | Missense Mutation | UCEC |