Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q91ZA3 | Pcca | Propionyl-CoA carboxylase alpha chain, mitochondrial … | Mus musculus (Mouse) | 724 aa |
Protein Details: Q91ZA3 (Pcca)
Protein Information
| Accession | Q91ZA3 |
|---|---|
| Protein Names | Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCase subunit alpha) (EC 6.4.1.3) (Propanoyl-CoA:carbon dioxide ligase subunit alpha) |
| Gene Symbol | Pcca |
| Organism | Mus musculus (Mouse) |
| Length | 724 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 34200797 34884899 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAGQWVRTVA11LLAARRHWRR21SSQQQLLGTL31KHAPVYSYQC41LVVSRSLSSV
51-10051EYEPKEKTFD61KILIANRGEI71ACRVIKTCKK81MGIKTVAIHS91DVDASSVHVK
101-150101MADEAVCVGP111APTSKSYLNM121DAIMEAIKKT131RAQAVHPGYG141FLSENKEFAK
151-200151RLAAEDVTFI161GPDTHAIQAM171GDKIESKLLA181KRAKVNTIPG191FDGVVKDADE
201-250201AVRIAREIGY211PVMIKASAGG221GGKGMRIAWD231DEETRDGFRF241SSQEAASSFG
251-300251DDRLLIEKFI261DNPRHIEIQV271LGDKHGNALW281LNERECSIQR291RNQKVVEEAP
301-350301SIFLDPETRQ311AMGEQAVALA321KAVKYSSAGT331VEFLVDSQKN341FYFLEMNTRL
351-400351QVEHPVTECI361TGLDLVQEMI371LVAKGYPLRH381KQEDIPISGW391AVECRVYAED
401-450401PYKSFGLPSI411GRLSQYQEPI421HLPGVRVDSG431IQPGSDISIY441YDPMISKLVT
451-500451YGSDRAEALK461RMEDALDNYV471IRGVTHNIPL481LREVIINTRF491VKGDISTKFL
501-550501SDVYPDGFKG511HTLTLSERNQ521LLAIASSVFV531ASQLRAQRFQ541EHSRVPVIRP
551-600551DVAKWELSVK561LHDEDHTVVA571SNNGPAFTVE581VDGSKLNVTS591TWNLASPLLS
601-650601VNVDGTQRTV611QCLSREAGGN621MSIQFLGTVY631KVHILTKLAA641ELNKFMLEKV
651-700651PKDTSSTLCS661PMPGVVVAVS671VKPGDMVAEG681QEICVIEAMK691MQNSMTAGKM
701-724701GKVKLVHCKA711GDTVGEGDLL721VELE
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 40 | - | - | - |
Deep-Palm: 0.90
|
|
| 72 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.87
|
|
| 78 | - | - | - |
Deep-Palm: 0.84
|
|
| 107 | SWISSPALM DBPTM CYSMODDB | Biotin carboxylase N-terminal domain |
Liver
(28526873)
|
Brain
(35358180)
|
Deep-Palm: 0.76
|
| 286 | - | - | - |
Deep-Palm: 0.87
|
|
| 359 | SWISSPALM DBPTM CYSMODDB | Carbamoyl-phosphate synthase L chain ATP binding domain |
Liver
(28526873)
|
Macrophage Raw 264.7
(29217618)
|
Deep-Palm: 0.95
|
| 394 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
| - |
Deep-Palm: 0.72
|
| 612 | Propionyl-coenzyme A carboxylase BT domain |
Brain
(34200797)
| - |
Deep-Palm: 0.91
|
|
| 659 | - | - | - |
Deep-Palm: 0.93
|
|
| 684 | - | - | - |
Deep-Palm: 0.90
|
|
| 708 | Biotin-requiring enzyme |
Brain
(34200797)
| - |
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.625
5
Liver
Specificity: 0.139
5/5 (100.0%)
3
Brain
Specificity: 0.083
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.679
19
Brain tissue (Mass)
Specificity: 0.528
19/56 (33.9%)
9
Macrophage Raw 264.7 (Mass)
Specificity: 0.250
9/10 (90.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.