Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q921F2 Tardbp TAR DNA-binding protein 43 (TDP-43) Mus musculus (Mouse) 414 aa

Protein Details: Q921F2 (Tardbp)

Protein Information
AccessionQ921F2
Protein NamesTAR DNA-binding protein 43 (TDP-43)
Gene SymbolTardbp
OrganismMus musculus (Mouse)
Length414 aa
IsoformsNo isoforms
Related PMIDs 28526873 29217618 29733200 34884899 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSEYIRVTED11ENDEPIEIPS21EDDGTVLLST31VTAQFPGACG41LRYRNPVSQC
51-10051MRGVRLVEGI61LHAPDAGWGN71LVYVVNYPKD81NKRKMDETDA91SSAVKVKRAV
101-150101QKTSDLIVLG111LPWKTTEQDL121KDYFSTFGEV131LMVQVKKDLK141TGHSKGFGFV
151-200151RFTEYETQVK161VMSQRHMIDG171RWCDCKLPNS181KQSPDEPLRS191RKVFVGRCTE
201-250201DMTAEELQQF211FCQYGEVVDV221FIPKPFRAFA231FVTFADDKVA241QSLCGEDLII
251-300251KGISVHISNA261EPKHNSNRQL271ERSGRFGGNP281GGFGNQGGFG291NSRGGGAGLG
301-350301NNQGGNMGGG311MNFGAFSINP321AMMAAAQAAL331QSSWGMMGML341ASQQNQSGPS
351-400351GNNQSQGSMQ361REPNQAFGSG371NNSYSGSNSG381APLGWGSASN391AGSGSGFNGG
401-414401FGSSMDSKSS411GWGM
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
39 TAR DNA-binding protein 43, N-terminal
brain (39008777)
MLE (39008777)
-
Deep-Palm: 0.97
50 SWISSPALM DBPTM CYSMODDB TAR DNA-binding protein 43, N-terminal TAR DNA-binding protein 43 N-terminal domain
Liver (28526873)
-
GPS-Palm: 0.94
Deep-Palm: 0.92
173 -
MLE (39008777)
-
Deep-Palm: 0.12
175 -
MLE (39008777)
-
Deep-Palm: 0.16
198 - - -
Deep-Palm: 0.75
212 - - -
Deep-Palm: 0.17
244 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Brain (35358180)
Deep-Palm: 0.87
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
6
Liver
Specificity: 0.353
6/6 (100.0%)
1
Raw 264.7
Specificity: 0.059
1/1 (100.0%)
1
Brain
Specificity: 0.059
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
9
Brain tissue (Mass)
Specificity: 0.529
9/56 (16.1%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine