Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q921H8 Acaa1a 3-ketoacyl-CoA thiolase A, peroxisomal (EC … Mus musculus (Mouse) 424 aa

Protein Details: Q921H8 (Acaa1a)

Protein Information
AccessionQ921H8
Protein Names3-ketoacyl-CoA thiolase A, peroxisomal (EC 2.3.1.16) (Acetyl-CoA C-myristoyltransferase) (EC 2.3.1.155) (Acetyl-CoA acyltransferase A) (EC 2.3.1.9) (Beta-ketothiolase A) (Peroxisomal 3-oxoacyl-CoA thiolase A)
Gene SymbolAcaa1a
OrganismMus musculus (Mouse)
Length424 aa
IsoformsNo isoforms
Related PMIDs 28526873 29660268 29733200 31772009 34884899 35358180 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MHRLQVVLGH11LAGRPESSSA21LQAAPCSARF31PQASASDVVV41VHGRRTPIGR
51-10051ASRGGFKNTT61PDELLSAVLT71AVLQDVRLKP81EQLGDISVGN91VLEPGAGAVM
101-150101ARIAQFLSGI111PETVPLSTVN121RQCSSGLQAV131ANIAGGIRNG141SYDIGMACGV
151-200151ESMSLSGMGN161PGNISSRLLE171SEKARDCLTP181MGMTSENVAE191RFGISRQKQD
201-250201DFALASQQKA211ASAQSRGCFR221AEIVPVTTTV231LDDKGDKKTI241TVSQDEGVRP
251-300251STTMQGLAKL261KPAFKDGGST271TAGNSSQVSD281GAAAVLLARR291SKAEELGLPI
301-350301LGVLRSYAVV311GVPPDVMGIG321PAYAIPAALQ331KAGLTVNDID341IFEINEAFAS
351-400351QAVYCVEKLG361IPAEKVNPLG371GAIALGHPLG381CTGARQVVTL391LNELKRRGRR
401-424401AYGVVSMCIG411TGMGAAAVFE421YPGN
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
26 - - -
Deep-Palm: 0.96
123 SWISSPALM DBPTM CYSMODDB Thiolase N-terminal domain
Forebrain (28680068)
-
Deep-Palm: 0.97
148 - - -
Deep-Palm: 0.60
177 SWISSPALM DBPTM CYSMODDB Thiolase N-terminal domain
Liver (28526873)
-
Deep-Palm: 0.97
218 - - -
GPS-Palm: 0.90
Deep-Palm: 0.93
355 - -
Liver (34884899)
Deep-Palm: 0.97
381 - -
Liver (37925639)
GPS-Palm: 0.90
Deep-Palm: 0.98
408 - - -
Deep-Palm: 0.97
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
6
Liver
Specificity: 0.600
6/6 (100.0%)
3
Brain
Specificity: 0.300
3/3 (100.0%)
1
NSC
Specificity: 0.100
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine