Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q922B1 Macrod1 ADP-ribose glycohydrolase MACROD1 (MACRO domain-containing … Mus musculus (Mouse) 323 aa

Protein Details: Q922B1 (Macrod1)

Protein Information
AccessionQ922B1
Protein NamesADP-ribose glycohydrolase MACROD1 (MACRO domain-containing protein 1) (O-acetyl-ADP-ribose deacetylase MACROD1) (EC 3.1.1.106) (Protein LRP16) ([Protein ADP-ribosylaspartate] hydrolase MACROD1) (EC 3.2.2.-) ([Protein ADP-ribosylglutamate] hydrolase MACROD1) (EC 3.2.2.-)
Gene SymbolMacrod1
OrganismMus musculus (Mouse)
Length323 aa
IsoformsNo isoforms
Related PMIDs 28526873 34200797 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSLQSQVSGR11LAQLRAAGQL21LVSLRPWPGR31SAGGPRPRGS41ACGPLVALGE
51-10051HGYCAWLSAG61VGAWGAAGRG71AWVRTWAPLA81MAAKVDLSTS91TDWKEAKSFL
101-150101KGLSDKQREE111HYFCKDFIKL121KKIPTWKETA131KGLAVKVEDP141KYKKDKQLNE
151-200151KISLYRGDIT161KLEVDAIVNA171ANSSLLGGGG181VDGCIHRAAG191SLLTDECRTL
201-250201QNCETGKAKI211TCGYRLPAKY221VIHTVGPIAV231GQPTASQAAE241LRSCYLSSLD
251-300251LLLEHRLRSV261AFPCISTGVF271GYPNEEAAEV281VLASLREWLE291QHKDKVDRLI
301-323301ICVFLEKDEG311IYRERLPHYF321PVA
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
42 - - -
Deep-Palm: 0.90
54 - - -
Deep-Palm: 0.92
114 - - -
Deep-Palm: 0.79
184 - - -
Deep-Palm: 0.97
197 SWISSPALM DBPTM CYSMODDB Macro domain
liver (26165157)
Liver (28526873)
Brain (35358180)
Deep-Palm: 0.81
203 - - -
Deep-Palm: 0.87
212 Macro domain
Brain (34200797)
-
Deep-Palm: 0.82
244 SWISSPALM DBPTM CYSMODDB Macro domain
liver (26165157)
Liver (28526873)
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.97
264 SWISSPALM DBPTM CYSMODDB Macro domain
Liver (28526873)
-
GPS-Palm: 0.89
Deep-Palm: 0.95
302 SWISSPALM DBPTM CYSMODDB -
liver (26165157)
-
GPS-Palm: 0.89
Deep-Palm: 0.83
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
4
Liver
Specificity: 0.308
4/4 (100.0%)
2
Brain
Specificity: 0.154
2/2 (100.0%)
2
Testis
Specificity: 0.154
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
5
Brain tissue (Mass)
Specificity: 0.385
5/56 (8.9%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine