Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q922Q8 Lrrc59 Leucine-rich repeat-containing protein 59 [Cleaved … Mus musculus (Mouse) 307 aa

Protein Details: Q922Q8 (Lrrc59)

Protein Information
AccessionQ922Q8
Protein NamesLeucine-rich repeat-containing protein 59 [Cleaved into: Leucine-rich repeat-containing protein 59, N-terminally processed]
Gene SymbolLrrc59
OrganismMus musculus (Mouse)
Length307 aa
IsoformsNo isoforms
Related PMIDs 28526873 29733200 34884899 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MTKAGSKGGN11LRDKLDGNEL21DLSLSDLNEV31PVKELAALPK41ATVLDLSCNK
51-10051LSTLPSDFCG61LTHLVKLDLS71KNKLQQLPAD81FGRLVNLQHL91DLLNNRLVTL
101-150101PVSFAQLKNL111KWLDLKDNPL121DPVLAKVAGD131CLDEKQCKQC141ANKVLQHMKA
151-200151VQADQERERQ161RRLEVEREAE171KKREAKQQAK181EAKERELRKR191EKAEEKERRR
201-250201KEYDAQKASK211REQEKKPKKE221ANQAPKSKSG231SRPRKPPPRK241HTRSWAVLKV
251-300251LLLLLLLCVA261GGLVVCRVTG271LHQQPLCTSV281NTIYDNAVQG291LRHHEILQWV
301-307301LQTDSQQ
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
48 SWISSPALM DBPTM CYSMODDB L domain-like Leucine rich repeat Leucine-rich repeat domain superfamily Leucine-rich repeat
Liver (28526873)
-
Deep-Palm: 0.98
59 SWISSPALM DBPTM CYSMODDB Leucine rich repeat
Liver (28526873)
Brain (35358180)
Deep-Palm: 0.97
131 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
-
Deep-Palm: 0.96
137 - - -
Deep-Palm: 0.85
140 - - -
Deep-Palm: 0.50
258 - - -
Deep-Palm: 0.99
266 - - -
Deep-Palm: 0.99
277 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Forebrain (28680068)
Brain (35358180)
Deep-Palm: 0.85
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
6
Liver
Specificity: 0.261
6/6 (100.0%)
2
Testis
Specificity: 0.087
2/2 (100.0%)
1
Brain
Specificity: 0.043
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.857
12
Brain tissue (Mass)
Specificity: 0.522
12/56 (21.4%)
2
Liver tissue (Mass)
Specificity: 0.087
2/8 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine