Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q923B6 Steap4 Metalloreductase STEAP4 (EC 1.16.1.-) (Dudulin-4) … Mus musculus (Mouse) 470 aa

Protein Details: Q923B6 (Steap4)

Protein Information
AccessionQ923B6
Protein NamesMetalloreductase STEAP4 (EC 1.16.1.-) (Dudulin-4) (Six-transmembrane epithelial antigen of prostate 4) (Tumor necrosis factor-alpha-induced adipose-related protein)
Gene SymbolSteap4
OrganismMus musculus (Mouse)
Length470 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MEKAHADEFP11LTTDSSEKQG21VVCIFGTGDF31GKSLGLKMLQ41CGYSIVFGSR
51-10051NPQVSSLLPR61GAEVLSYSEA71ASKSDIIILA81MHREHYDSLT91ELVDYLKGKV
101-150101LVDVSNNRKI111NQYPESNAEY121LAQLEPGAHV131VKAFNTISAW141ALQSGTLDAS
151-200151RQVFVCGNDS161KAKQRVMDIA171RTLGLTPLDQ181GSLMAASEIE191NYPLQLFPMW
201-250201RFPFYLSSVL211CVFFFVYCAI221REVIYPYVNG231KTDATYRLAI241SIPNRVFPIT
251-300251ALILLALVYL261PGILAAILQL271YRGTKYRRFP281NWLDHWMLCR291KQLGLVALGF
301-350301AFLHVIYTLV311IPIRYYVRWR321LRNATITQAL331TNKDSPFITS341YAWINDSYLA
351-400351LGILGFFLFL361LLGITSLPSV371SNMVNWREFR381FVQSKLGYLT391LVLCTAHTLV
401-450401YGGKRFLSPS411ILRWSLPSAY421ILALVIPCAV431LVLKCILIMP441CIDKTLTRIR
451-470451QGWERNSKYT461QSALNGKSDI
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
23 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Liver (34884899)
Deep-Palm: 0.95
41 STEAP family metalloreductases - -
GPS-Palm: 0.91
Deep-Palm: 0.94
156 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
-
Deep-Palm: 0.95
211 - - -
Deep-Palm: 0.06
218 - - -
Deep-Palm: 0.07
289 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
-
Deep-Palm: 0.81
394 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
-
Deep-Palm: 0.92
428 - - -
Deep-Palm: 0.89
435 -
Liver (28526873)
-
Deep-Palm: 0.94
441 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
-
GPS-Palm: 0.95
Deep-Palm: 0.94
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
6
Liver
Specificity: 0.600
6/6 (100.0%)
2
Testis
Specificity: 0.200
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Liver tissue (Mass)
Specificity: 0.200
2/8 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine